In the News

Warren paper examines dysfunction in dopamine system, influence on depression in older adults

Warren D. Taylor, M.D., MHSc, James G Blakemore Professor of Psychiatry, served as lead author of a new publication proposing how dysfunction in the dopamine system may influence depression in older adults. This may influence risk for depression but also serve as a new target for treatment.  The manuscripts provides the rationale for a current multi-site study being conducted at Vanderbilt examining the effect of levodopa (Sinemet) on late-life depression. The paper appears in the journal Molecular Psychiatry. 

Christman, Taylor article published in Translational Psychiatry

Fourth-year resident in General Psychiatry Seth Christman, MD, and James G Blakemore Professor of Psychiatry and Behavioral Sciences Warren Taylor, MD, MHSc, recently published the article "Accelerated brain aging predicts impaired cognitive performance and greater disability in geriatric but not midlife adult depression" in the journal Translational Psychiatry.

Taylor, Blackford publish manuscript on mental health of clinicians treating COVID-19

Warren D. Taylor, M.D., MHSc, and Jennifer U. Blackford, Ph.D., professors of Psychiatry & Behavioral Sciences, have written a new publication detailing the effect of the COVID-19 pandemic on the mental health of front-line clinicians.  The manuscript, published in The Annals of Internal Medicine, describes physiological changes that occur with stress that lead to burnout and mental health disorders.  It challenges many providers' reluctance to seek treatment and proposes strategies to maintain mental health.

Taylor co-authors JAMA Psychiatry article on age-related mental disorders

As the percentage of U.S. adults older than 65 years continues to grow, so too does the need for preventing mental illness among older adults as well as improving clinical services and outcomes for older patients with psychiatric disorders. Psychiatry's obligation to treat this population, and an agenda for research and enhancement of clinical services, is outlined by Warren D. Taylor, M.D., M.H.Sc., James G. Blakemore Professor of Psychiatry and Director, Division of General Psychiatry, and Charles F.

Nicotine patch shows promise in treating late-life depression

A Vanderbilt University Medical Center pilot study of treating late-life depression in nonsmokers with transdermal nicotine (nicotine patch) has yielded some promising results, but the study’s author cautions that more study is needed. Late-life depression — depression that occurs in adults 60 years or older — is characterized by poor response to antidepressant medications and often memory issues. About half of those treated for late-life depression fail to respond to initial treatments.

Deng, Taylor team up, publish paper on adults and antidepressants

Yi Deng, M.D., resident in Psychiatry & Behavioral Sciences, and Warren Taylor, M.D., professor of Psychiatry & Behavioral Sciences, have worked together to publish a paper titled "Predictors of recurrence in remitted late-life depression" in the journal Depression and Anxiety. The paper examines factors in older adults that may predict the return of depression after successful antidepressant treatment. 
 
 Click here to view the abstract.

Riddle, Taylor article published in American Journal of Geriatric Psychiatry

Meghan Riddle, M.D., Assistant Professor of Psychiatry & Behavioral Sciences, and Warren Taylor, M.D., Professor of Psychiatry & Behavioral Sciences, were among the authors of an article titled "Longitudinal cognitive outcomes of clinical phenotypes of late-life depression," published recently in the March issue of The American Journal of Geriatric Psychiatry.

Taylor co-authors paper on cerebral blood flow, cerebrovascular reactivity as predictors of antidepressant response

Warren D. Taylor, M.D., Associate Professor of Psychiatry & Behavioral Sciences, served as co-author on a new paper titled "Frontocingulate cerebral blood flow and cerebrovascular reactivity as predictors of antidepressant response in late-life depression." The paper appears in the Journal of Affective Disorders. The study was directed by Dr. Margarita Abi Zeid Daou, a PGY4 resident in the Department of Psychiatry & Behavioral Sciences, mentored by Dr. Taylor.

Taylor receives NIMH grant toward efforts to mentor young scientists, researchers

Warren D Taylor, M.D., MHSc., Associate Professor of Psychiatry and Director of the Mood Disorders Program Center for Cognitive Medicine, was recently awarded NIMH funding toward his K24 Midcareer Investigator Award in Patient-Oriented Research. This proposal will support Dr. Taylor in his efforts to mentor young scientists and researchers, from medical students to medical residents to junior faculty.  

Taylor article on early life stress on depression published in Psychological Medicine

Warren D. Taylor, M.D., MHSc, Associate Professor of Psychiatry and Investigator in the Vanderbilt Center for Cognitive Medicine, was one of several authors of the recently published article "Effects of early life stress on depression, cognitive performance, and brain morphology." The article appears in the journal Psychological Medicine.
 
 Click here to view the abstract.