Department of Pathology, Microbiology and Immunology

Biochemistry and molecular biology of HIV infection; antiviral mechanisms

Immune response to Helicobacter pylori

Clinical trials, Pediatric Transfusion Medicine, blood utilization

Pathogenesis of hematopoietic malignancies

Mechanisms of bacterial immune evasion in the female reproductive tract

Post-transcriptional gene regulation in innate immunity and cellular stress

Functional genomic and epigenetic approaches to understand gene regulation

Translational cancer research focused on molecular therapeutics, onco-immunology & bioinformatics

Mechanisms by which growth factors mediate and influence organ formation during embryogenesis

Human immunology, human genetics, infectious diseases, molecular biology, primary immunodeficiencies (PID), immunogenetics

Translational research in acute lung injury and sepsis focusing on molecular mechanisms

Microbiology, Genomics, Evolution, Population Genetics

Immunomodulatory therapies for the prevention of infection and sepsis following a severe burn injury

B cell, T cell, autoimmunity, type 1 diabetes, arthritis, microbiome

Transfusion medicine/blood banking, clinical pathology

Signal transduction, transcription regulation mechanisms

Symbiosis, Microbiome, Virology, Evolution, Genomics, Origin of Species

Clinical dermatology, dermatopathology, cutaneous neoplasms

Linking gut microbiota, host metabolism, and disease

Interaction between host and pathogen during invasive bacterial infections

Orthopedic pathology, sarcoma, bone and soft tissue tumors

Macular degeneration, diabetic retinopathy, gene therapy for retinal diseases, retinal detachment & repair

Immune response, cellular metabolism & tumor progression

Cytopathology, anatomic pathology and surgical pathology

Pediatric pathology

Bacteria-host interactions, bacterial toxins, helicobacter pylori, and gastric cancer

Innate and acquired immunity in inflammatory arthritis, myositis, scleroderma, fibromyalgia, pain

Human B cell and antibody responses to infections

Replication, cell biology, and pathogenesis of coronaviruses; emerging viruses in biodefense

Investigating the role of Factor XI in coagulation and thrombosis

Cellular-molecular biology of cardiometabolic disease.

Hematopathology and medical education

Molecular biolody and immunopathogenesis of chronic inflammatory states, particularly sarcoidosis

Global health education and pathology

Thoracic pulmonary pathology cytopathology

Head and neck pathology, cytopathology

Allied Health Programs

Structure and function of large clostridial cytotoxins

Progression of kidney disease crosstalk PAI-1 regression of sclerosis podocytes regeneration stem cells

Helicobacter pylori,  microbiology, cellular, molecular, and structural biology, protein, Acinetobacter baumannii

Biochemistry, enzyme action, gene regulation, knockout, mouse, polymorphism, protein structure

Computational immunology and virology

Mechanisms of prostate cancer progression and recurrence; prostate cancer biomarker discovery

Mechanisms regulating intestinal immunity

Creation of tutorials and other teaching materials for users of clinical flow cytometers

Clinicopathologic and immunophenotypic prognostic markers, the clarification of diagnostic challenges in genitourinary malignancies

AIDS, HIV, pharmacogenomics, tuberculosis

Bacterial Signal Transduction and Multicellular Behavior in Uropathogens

Pathogenesis of myelodysplastic syndrome and acute myeloid leukemia

Growth factor and cytokine receptors on T lymphocytes

Graduate medical education

The structure and function of type IV collagen, the major constituent of basement membranes (BMs)

Antimicrobial resistance, Bacterial pathogenesis, Diagnostic testing, Clinical microbiology

Cancer, precision medicine, computational biology, machine learning, cell signaling, chemical biology, single cell tools

Autopsy, Gastrointestinal, Liver and Pancreatic pathology

Atherosclerosis, lipid, cholesterol, macrophage

Histopathology and immunopathology of pediatric viral pneumonias, etiology and pathogenesis of idiopathic interstitial lung diseases, cytologic diagnosis of disease

Antigen presentation and recognition by immune cells

Hematopathology, lymphoma, and leukemia

Cellular immune responses directed against viral and bacterial pathogens; therapeutic immunization, HIV vaccines

Renal pathology and autopsy pathology

Oncogenic Viruses, RNA-based mechanisms of antiviral and antitumor immunity, epigenomics, CRISPR screens

Hematology and oncology

Head & neck surgery, squamous cell carcinoma, otolaryngology

neutralization of the Clostridium difficile toxins by antibodies and small molecule inhibitors

Structures and molecular mechanisms of bacterial toxins

Signaling pathways involved in mammary gland homeostasis and breast cancer

Head and Neck Pathology; Squamous Cell Carcinoma; Human Papillomavirus; Sinonasal Tumors

Diagnostic pediatric pathology and neuropathology 

Functional genomics and systems biology analysis of the immune response and translation

Renal Pathology

Immunological mechanisms of autoimmunity in atherosclerosis

Immunometabolism & Metabolic Diseases, Tumor Biology & Tumor Immunology

C. difficile bacterial toxin pathogenesis and the mechanisms of microbially influenced colorectal cancer tumorigenesis

Human immunology, genetics, T cells, innate immunity, flow and mass cytometry, host-microbe interactions, microbiome, bioinformatics

Hematopathology

Pediatric Pathology and Hematopathology

Anatomic surgical and diagnostic cytopathology

Head and neck pathology, squamous cell carcinoma, human papillomavirus, thoracic pathology, non-neoplastic lung disease; lung cancer

DNA replication, mutagenesis, and evolution

Innate immunity initiated by activation of Toll-Like Receptor 3, next generation sequencing applications, pathogenesis of intracellular microbes

Glioblastoma, glioma, IDH mutation

Immune regulation in autoimmunity and transplantation

Regulation of cell proliferation by growth factors, oncogenes, growth inhibitors and tumor suppressor genes

Tumor dysregulation of apoptosis pathways leading to T cell induced apoptosis resistance

Estrogen, testosterone, sex hormones, T cells, innate lymphoid cells, asthma, allergy

Clinical chemistry, point-of-care testing, laboratory automation, information management, clinical toxicology and therapeutic drug monitoring

Innate immune responses to bacterial pathogens in the lung

Double-stranded RNA virus tropism and diversity mechanisms

Mucosal immunology, IEL, iCD8alpha, osteopontin, granzyme

Reproductive medicine, human endometium, endometrial dysfunction, endometriosis, progesterone action

Renal amyloidosis, light chain deposition disease, diabetic nephropathy, CNS vasculitis, and restless legs syndrome

Allergically-mediated and virally-induced lung inflammation

Pathogenesis, helicobacter pylori, gastric cancer, carcinogenesis, infectious disease, bacterial pathogenesis, inflammation, malignancy

Cancer, tumor immunology, T cells, epigenetics, autoimmunity, differentiation, single-cell analysis, flow cytometry

HIV, drug safety, pharmacology, personalized medicine, drug hypersensitivity, HLA, immunopathogenesis, severe H1N109 disease

Molecular investigations of familial disorders

Cytogenetics and clinical genomics

Lung, miRNA, exRNA (extracellular RNA), extracellular vesicles, allergy, asthma, Th2

T cell metabolism in inflammation and anti-tumor immunity

Amphibian immune defenses against an ancient fungal pathogen

GI, liver and pancreas pathology

Breast cancer and proliferative breast disease

Clinical Microbiology, Molecular Diagnostics, Opportunistic pathogens, Microbe-microbe interactions, Personalized microbiology, Urinary tract infections

The role of coagulation in normal and pathologic orthopaedic related wounds

Cytopathology

Proteomics of sarcomas, bone metastasis and tissue engineering

Lipids, metabolism, cystic fibrosis, hematopathology, flow cytometry hematologic malignancy, leukemia, lymphoma

Understanding host defense in pre-existing inflammatory conditions

Flow cytometry, including multivariate modeling

Mechanisms of sepsis-induced systemic inflammation and organ injury with emphasis on the roles of natural killer (NK) and T lymphocytes

Comparative medicine

Factors and processes involved in the battle for metal between bacterial pathogens and their hosts

Dengue virus, vaccines, immunology, viral pathogenesis

Genomics, molecular biology, genetics and biochemistry of HIV-1 infection

Structural Biology of virulence factors, host-pathogen relationship, and cytoskeletal regulation

Mechanism of CNS demyelination

Neonatal pulmonary pathology

Pathogenesis of chlamydia pneumoniae

Cancer, breast cancer, genomics, ChIP-seq, RNAseq, mutations, chromatin, transcription, epigenetics

Lipoprotein assembly, lipid droplet formation, adipocyte biology

Mechanisms that regulate immune tolerance and why they fail in autoimmune disorders such at type 1 diabetes

Hematology and oncology

Role of innate-type regulatory lymphocytes in health and chronic inflammatory diseases

Regulation of blood coagulation proteolytic enzymes

Clinical molecular genetics

Diseases of nonhuman primates, Animal models of obesity and metabolic syndrome

Translational research in acute lung injury and lung transplantation

Histopathology of gastrointestinal and hepatic diseases and mouse models of GI cancer

Cancer invasion, membrane trafficking, cytoskeleton, systems biology, secreted exosomes, extracellular RNA

Molecular and immunologic mechanisms of thyroid cancer invasion and metastasis

Hemophilia and hemostatic disorders in pediatric patients

Clinical cytogenetics and molecular diagnostics in cancer

Clinical Chemistry, Diagnostic Stewardship, Endocrinology, Medical Education, and Point of Care Testing

Host immune response to the gastric pathogen Helicobacter pylori 

Interactions between the immune and metabolic systems, whole body metabolism

Clinical cytogenetics including cytogenomic array

Animal models of human disease

Molecular basis of cell adhesion to collagen with a focus on the alpha2 beta1 integrin

Resilience mechanism of gut commensals, metabolic targeting of gut microbes to promote commensal resilience, and the roles of bacterial toxin in promoting colorectal cancer development

Mechanisms by which normal and malignant cells regulate programed cell death or apoptosis following DNA damage

Comparative medicine