Antimicrobial resistance, Bacterial pathogenesis, Diagnostic testing, Clinical microbiology
Antimicrobial resistance (AMR) is one of the most pressing concerns in infectious diseases, if not all of medicine. A major dilemma in this scenario is the technologies relied to detect AMR infections are based on methods developed a century ago. More accurate and rapid methods are needed to curtail the spread of AMR and also improve patient outcomes. The Humphries laboratory evaluates methods that improve the speed and accuracy of identifying antibiotic-resistant bacteria infecting patients along with the impact such improved technologies may have on patient care. Additionally, our laboratory investigates novel AMR mechanisms in clinical bacterial isolates as they evolve in real time, and novel antimicrobials designed to treat these infections.