Travis Hassell, MD, PhD

Travis
Hassell
MD, PhD
Assistant Professor
Neurology

Dr. Travis Hassell is an Assistant Professor of Neurology specializing in Movement Disorders at Vanderbilt University Medical Center. His clinical practice and research focuses both on movement disorders and bioengineering, with an emphasis on developing new device technologies such as adaptive deep brain stimulation (DBS). Dr. Hassell also provides instruction in inpatient and outpatient clinical settings for medical students and residents. He is currently a member of the North American Neuromodulation Society, the Movement Disorders Society, the American Academy of Neurology, and the Biomedical Engineering Society (BMES). 

Prior to his current appointment, Dr. Hassell completed a Movement Disorders Fellowship at VUMC. He earned his MD from the Indiana University School of Medicine in 2012, and subsequently completed his medical internship at St. Elizabeth Medical Center (Youngstown, OH) and Neurology residency at Indiana University (Indianapolis, IN), serving as Chief Resident his final year. Dr. Hassell earned his doctorate in Biomedical Engineering from Purdue University (West Lafayette, IN), graduating summa cum laude with a thesis studying devices for real-time monitoring of central nervous system recovery. He received his BS in Biological Engineering (summa cum laude) from the University of Missouri – Columbia. 

Dr. Hassell’s research interests focus on the intersection of engineering and the treatment of neurological movement disorders. He is currently participating as Primary Investigator (PI) or Sub-PI in clinical trials studying DBS devices.

Ye Han, PhD

Ye
Han
PhD
Research Associate Professor
Neurology

Dr. Ye Han is a Research Associate Professor of Neurology at Vanderbilt University Medical Center, specializing in molecular/cellular mechanism studies of neurological disorders. Her research focuses on studying the structure and function of HCN channels and its auxiliary subunit, TRIP8b in the dorsal hippocampus and related neural circuitry with the hope of finding new therapies to treat neurological diseases. Dr. Han completed her PhD in molecular biology in the laboratory of Drs. Kang Chong and Zhihong Xu at the Chinese Academy of Sciences.

Dr. Han’s research has resulted in important contributions to the understanding of the role of TRIP8b in regulating HCN channel function. In particular, she was the first to report that TRIP8b and HCN interact at two distinct sites and that cAMP may directly compete for binding the HCN CNBD domain to control HCN channel trafficking and function. Subsequently, she identified the first known small molecule inhibitor of the interaction between TRIP8b and HCN using high throughput screening techniques. She recently demonstrated that modulating the TRIP8b-HCN interaction bidirectionally influences channel trafficking and antidepressant-like behavior.

Dr. Han’s current research focuses on developing novel antidepressant therapies based on the lab’s discovery that TRIP8b, an auxiliary subunit of HCN channels, regulates antidepressant-like behavior. She previously demonstrated that TRIP8b regulates HCN channel surface expression and subcellular localization by binding to pore forming subunits at two distinct locations. She subsequently examined the structure-function relationship of TRIP8b mediated HCN channel trafficking using viral mediated rescue experiments in TRIP8b knockout animals. She found that restoring TRIP8b expression to the hippocampi of TRIP8b knockout animals impaired the animal’s performance on screening tests for antidepressant efficacy. She also showed that reducing TRIP8b mediated HCN channel trafficking in the hippocampus improved the animal’s performance on the same tests. These results indicated that inhibiting TRIP8b mediated HCN channel trafficking is a promising target for novel antidepressant therapies.

Mallory Hacker, PhD, MSCI

Mallory
Hacker
PhD, MSCI
Assistant Professor
Neurology

Dr. Hacker is Assistant Professor of Neurology at Vanderbilt University Medical Center. She received the 2019 Kumar New Investigator Award from the North American Neuromodulation Society. She has received funding from the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute on Aging (NIA), the Department of Defense's Congressionally Directed Medical Research Program (CDMRP), the Michael J. Fox Foundation for Parkinson’s Research (MJFF), and the American Parkinson Disease Association (APDA). 

Dr. Hacker earned a B.S. in Chemistry in 2007 from the University of Tennessee at Chattanooga. She attended Vanderbilt University where she earned a Ph.D. in Cell and Developmental Biology studying neurodegenerative pathways arising from Coenzyme Q deficiency in 2013. She received postdoctoral training in neurology clinical research at Vanderbilt University Medical Center (VUMC) and was a visiting assistant professor at the Bloomberg School of Public Health at Johns Hopkins University in 2016. She completed the Vanderbilt School of Medicine Master of Science in Clinical Investigation (MSCI) program in 2019.

Dr. Hacker’s research focuses on understanding the effects of deep brain stimulation (DBS) in very early-stage Parkinson’s disease patients and studying objective methods to evaluate Parkinson’s disease progression. She also investigates the prevalence and impact of spasticity in the long-term care setting as well as ways to improve its screening, referral, and treatment. 

Newswise: Sweet-Spot Brain Stimulation May Halt Parkinson’s Progression

VUMC Reporter: Deep brain sweet spot might be key to halt Parkinson’s

Neurology Advisor: Benefits of Deep Brain Stimulation for Early Stage Parkinson Disease

Technology Networks: 5-year Study Shows the Long-term Efficacy of Deep Brain Stimulation in Parkinson's

Medical Xpress: Nursing home study reveals 'woeful' underdiagnosis of spasticity

VUMC Discover: Reducing Untreated Spasticity in the Elderly

VUMC Reporter: Neuromodulation Society honors Hacker’s Parkinson’s research

The Tennessean: For Parkinson’s patients, a surreal brain surgery offers new hope

VUMC Reporter: DBS treatment may slow tremor progression in early-stage Parkinson’s patients

VUMC Reporter: Trial to test whether DBS slows Parkinson’s progression

 

 

Kevin Haas, MD, PhD

Kevin
Haas
MD, PhD
Division Chief
Epilepsy
Clinical Director
Epilepsy Surgery
Professor
Neurology

Dr. Kevin Haas joined the Vanderbilt Neurology Department faculty in 2004. His clinical focus is epilepsy and he serves as Clinical Director of the Epilepsy Surgery Program and as EEG Laboratory Director.  He rotates as an attending physician on the Neuro-ICU EEG and Epilepsy Monitoring Unit services. He is board certified in Neurology, Epilepsy, and Epilepsy Monitoring.  Dr. Haas is a fellow of the American Epilepsy Society, a fellow of the American Neurological Association, and a member of the American Academy of Neurology.

Dr. Haas earned his BS in biomedical engineering from Duke University in 1991, graduating magna cum laude with distinction. His completed his graduate and medical school training at the University of Michigan, where he earned his PhD degree in neuroscience in 1998 and MD degree in 1999. At Emory University, he completed his internal medicine internship in 2000, neurology residency in 2003, and clinical neurophysiology fellowship with an emphasis in epilepsy in 2004. He served as chief resident in neurology for the 2002-2003 medical year.

Dr. Haas’s clinical research projects focus on epilepsy surgery, ICU-EEG monitoring, epilepsy genetics, and status epilepticus. He is the Vanderbilt site principal investigator for the Critical Care EEG Consortium. In addition, he currently serves as the site principal investigator for multiple clinical trials evaluating new antiepileptic drugs and devices for diagnosis and treatment of medication-resistant epilepsy.  

Dr. Haas’s past research has focused on GABA-A receptor physiology, synaptic roles of ubiquitination, and epilepsy in Angelman syndrome. He is an author on numerous original articles in these fields.

Sarah Graves, MSN, FNP-BC

Sarah
Graves
M.S.
Assistant
Neurology

Sarah Graves is a family nurse practitioner in the Department of Neurology at Vanderbilt University Medical Center, a position she has held since 2016. In her role, she collaborates with a multidisciplinary team to manage the outpatient General Neurology patient population. She assesses, diagnoses and manages patients with a variety of neurological conditions including Alzheimer’s disease, Parkinson’s disease, headache, migraine, essential tremor, multiple sclerosis, and stroke. 

Prior to her current position in the outpatient clinic, Sarah also served as a critical care nurse in the Neurology ICU at VUMC. She received her BSN at Florida Gulf Coast University, and later earned her MSN from Belmont University in 2015. 

Research Presentations

Presented at the 11th Annual Cleveland Clinic Nursing Research Conference in Aurora, OH. Balance, C., Graves, S., Harvey, M., Lucas, E., & Smith, A. (2014). Strategies for medication adherence in patients with type 2 diabetes mellitus: a system review.

Martin J. Gallagher, MD, PhD

Martin
J.
Gallagher
MD, PhD
Associate Professor
Neurology
Vice Chair
Basic Science Research

Dr. Gallagher is currently Associate Professor of Neurology at Vanderbilt University Medical Center, with a predominant clinical focus in the medical and surgical treatment of patients with epilepsy. He is board certified by both the American Board of Psychiatry and Neurology in three specialties, Neurology, Clinical Neurophysiology, and Epilepsy Monitoring. 

Dr. Gallagher earned his BS in chemistry from the University of Notre Dame in 1989, graduating summa cum laude. He was a visiting scholar in neurobiology at Harvard University Medical School from 1992 to 1996, and earned a PhD in molecular biophysics and an MD from Washington University in 1997. He began his postgraduate training with an internship in internal medicine at Washington University, completed a neurology residency at Washington University in 2001, and a surgical epilepsy fellowship at Washington University from 2001 to 2002. Dr. Gallagher became an instructor of Neurology at Washington University in 2001 and joined the faculty at Vanderbilt University Medical Center as assistant professor of Neurology in 2002 and was promoted to associate professor (tenured) in 2010.

Dr. Gallagher’s main research interest is the elucidation of the interactions between epilepsy genes and environmental factors, such as traumatic brain injury, that promote the formation of epileptic circuits and that inhibit the normal functioning of cognitive networks. He uses electrophysiological techniques coupled with advanced signal processing analyses to interrogate the networks and then employs molecular and electrical neuromodulation approaches to restore normal neurophysiological functioning. 

Dr. Gallagher earned his B.S. in chemistry from the University of Notre Dame in 1989, graduating summa cum laude. He was a visiting scholar in neurobiology at Harvard University Medical School from 1992 to 1996, and earned a Ph.D. in molecular biophysics and an M.D. from Washington University in 1997. He began his postgraduate training with an internship in internal medicine at Washington University, completed a neurology residency at Washington University in 2001, and a surgical epilepsy fellowship at Washington University from 2001 to 2002. Dr. Gallagher became an instructor of Neurology at Washington University in 2001 and joined the faculty at Vanderbilt University Medical Center as assistant professor of Neurology in 2002.

Dr. Gallagher is board certified by both the American Board of Psychiatry and Neurology and the American Board of Clinical Neurophysiology in three specialties, Neurology, Clinical Neurophysiology, and Epilepsy Monitoring, and he is currently an attending physician at Vanderbilt University Medical Center. His main research interest is in the elucidation of the molecular mechanisms by which mutations in epilepsy genes cause disease. His predominant clinical focus is in the medical and surgical treatment of patients with epilepsy.

Kenneth J. Gaines, MD, MBA

Kenneth
J.
Gaines
MD, PhD
Professor
Clinical Neurology

Dr. Kenneth Gaines is currently Professor of Neurology specializing in stroke medicine at Vanderbilt University Medical Center (VUMC) and the Vanderbilt School of Medicine. He also is a Scholar for the Center for Health Services Research. He is a Fellow of the American Academy of Neurology (FAAN), American EEG Society, the Stroke Council of the American Heart Association, and the American Society of Physician Executives, in addition to numerous other professional memberships. Dr. Gaines is also currently a hospital staff neurologist for Ochsner Clinic Foundation in New Orleans, LA, as well as over 30 additional hospitals via telemedicine. He is a current reviewer for Lancet Neurology and Journal for Neurological Sciences.

Dr. Gaines is the recipient of several honors and awards, including System Physician of the Year for Oschner Clinic Foundation (2010), Innovative Project of the Year for Oschner Clinic Foundation (2011), serving as a Governor-appointed Commissioner for the Louisiana Emergency Response Network (2012-2016), and an election to the Palatucci Leadership Forum for the American Academy of Neurology (2004). Throughout his career, Dr. Gaines has held positions in numerous leadership offices and committees, currently participating in the Telemedicine Work Group for the American Academy of Neurology, the Hospital Alliance of Tennessee Telemedicine Task Force, and the Tennessee Department of Health Stroke Task Force.

Prior to his tenure at Vanderbilt, which began in 2015, Dr. Gaines served in a number of academic positions at institutions including the University of Queensland (Brisbane, Australia), Wright State University, Louisiana State University, University of South Carolina, Meharry Medical College, Michigan State University, University of Tennessee, and the University of Mississippi. In addition to his academic roles, his clinical experience includes private practice, hospital staff appointments, telemedicine, and consulting neurology. 

Dr. Gaines earned his MD from the University of Tennessee, followed by his Neurology residency and a Fellowship in Neurophysiology, also at the University of Tennessee. He later earned his MBA degree from the University of Memphis.

Dr. Gaines has acted as Principal Investigator or Co-Investigator on dozens of clinical trials and studies throughout his career, both industry-sponsored and NIH funded. He is currently Co-Investigator for a study on rural ambulance telemedicine sponsored by the U.S. Department of Agriculture, and a National Principal Investigator for a C3FIT (Comprehensive, Coordinated, Collaborative, Family-focused, Integrated, Technology Enabled) Stroke Care Delivery Design Randomized Comparative Effectiveness Trial.

Michael Froehler, MD, PhD

Michael
Froehler
MD, PhD
Associate Professor
Neurology

As a neuro interventionalist and stroke neurologist, Dr. Froehler cares for patients with brain aneurysms, AVMs, arterial narrowing in the head and neck, and other related cerebrovascular diseases. 

Dr. Froehler obtained his MD from the University of Rochester, where he also earned a PhD in neuroscience. He then performed internship and residency in neurology at Johns Hopkins, before moving to UCLA for fellowship training in vascular neurology and then interventional neuroradiology. He then joined the faculty at the University of Iowa before coming to Vanderbilt in 2013. He is now part of the Vanderbilt Cerebrovascular Service. 

Dr. Froehler maintains an active research program, and is currently the Vanderbilt PI for the NIH-sponsored StrokeNet – a national network for clinical research in cerebrovascular disease. 

John Y. Fang, MD

John
Y.
Fang
MD
Associate Professor
Neurology

Dr. Fang is Associate Professor of Neurology at Vanderbilt University Medical Center. At Vanderbilt since 1998, Dr. Fang focuses on the treatment of early Parkinson's disease and other movement disorders. He is also a staff physician at the VA Tennessee Valley Healthcare System.

From 1995-98, Dr. Fang served in the Public Health Service, working in the Clinical Pharmacology Section of the Experimental Therapeutics Branch of the National Institute of Neurologic Disorders and Stroke, focusing on clinical studies in Parkinson's disease and other neurodegenerative disorders.

Dr. Fang earned a BS degree, with Distinction, from the Pennsylvania State University in 1989 and received his MD from Jefferson Medical College in 1991. He completed an internship in Internal Medicine at Bryn Mawr Hospital in Bryn Mawr, PA (1991-92), and performed his residency in Neurology at Thomas Jefferson University Hospital in Philadelphia, PA (1992-95) where he was Chief Resident.

Dr. Fang’s research interest is in the treatment of Parkinson's disease (and other movement disorders) and in particular conducting clinical trials to delay the progression to disability in neurodegenerative conditions. Through a combination of local and international studies, his research work is geared towards identifying early interventions that may lessen disability over time.  Additionally, identification of markers of disease and disease severity may allow simpler studies to be done at lower cost. Studying the use of these technologies may allow better diagnostic accuracy and better treatments over time.

Wiaam Falouji, MBBS

Wiaam
Falouji
MBBS
Assistant Professor
Clinical Neurology

Dr. Wiaam Falouji is a Clinical Assistant Professor of Neurology at Vanderbilt University Medical Center. She diagnoses and manages patients in both inpatient and outpatient settings with a full range of neurological disorders, including ADD, ADHD, headaches, dementia, seizure disorders, stroke, neuropathy, Parkinson’s disease, Huntington’s disease, Multiple Sclerosis, neuromuscular disorders, movement disorders, and disorders of the spine. Performs and interprets electromyogram (EMG) and nerve conduction studies, and interprets electroencephalogram (EEG). She regularly presents lectures in the academic neurology/medical setting, as well as for the general public. 

Prior to her appointment at Vanderbilt, Dr. Falouji worked as a private practice neurologist. She completed her Neurology residency, serving as chief resident her final year, at George Washington University. Subsequently, she completed a fellowship in Neurophysiology (with a focus on EEG/EMG) at the University of Mississippi.