Psychiatry Grand Rounds 4/21 | Orr Lecture in Addiction Psychiatry

Orr Lecture AY23

"Long-term retention on buprenorphine and the OUD Cascade of Care"

About the Speaker:

Arthur Robin Williams MD, MBE
Assistant Professor, Division on Substance Use Disorders
Columbia University Department of Psychiatry
Research Scientist, New York State Psychiatric Institute


The activity is designed to help the learner

1.    Describe the evidence base for clinical benefits from long-term retention on buprenorphine
2.    Identify quality measures that are applicable to the treatment of OUD
3.    List key stages of the OUD Cascade of Care
4.    Describe the relationship between retention in OBOT treatment settings and patterns of opioid use over time 



Dramatic increases in overdose deaths in the US have created an urgent need to improve access to and retention in evidence-based care for opioid use disorder (OUD) with medication (MOUD), under the OUD Cascade of Care framework. The Cascade public health framework emphasizes key stages or transitions during the treatment of individuals with OUD to reduce risks of adverse outcomes: critically, successful MOUD initiation and long-term retention. However, it has thus far been agnostic towards concurrent opioid use. Patients with opioid use in care will likely experience attenuated risk reductions following treatment discontinuation. My goal is to establish an empirical evidence base to inform clinical evaluations of patient risks (e.g. adverse outcomes including overdose) at the individual level to inform care pathways. Against the scale and gravity of the evolving opioid epidemic, it is vital that clinical and policy strategies are informed by careful consideration of rigorous analyses of empirical data with large, usual-care populations.


CME/CE credit for Psychiatry Grand Rounds is only available during the live feed time and for a brief time immediately following. The code for this week's session is displayed at the opening and closing of the meeting and also in the Chair's Office Account Name during the meeting.


For CME/CE information about this session, please visit:


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Meeting ID: 278 187 060 202 
Passcode: 3qbe8B 



This talk is sponsored by the
Orr Lecture Fund
Department of Psychiatry and Behavioral Sciences 

This educational activity received no commercial support.