Molemolemo: Building Research Administration Excellence in South Africa
Under the program, Molemolemo: Building Research Administration Excellence in South Africa, grant administrators from the Vanderbilt Institute for Global facilitate advanced research capacity through training and implementation of a structured grants management course with administrative leaders from Vanderbilt University Medical Center (VUMC). A significant focus and output of the collaboration with Aurum is the in-house development of a structured grants management training course for non-US-based organizations, which includes essential and elective modules.
Martin Were joins team to develop point-of-care detection of jaundice in newborns for all skin tones
Aurum awarded NIH grant to boost research administration
Vanderbilt-Zambia Cancer Research Training Program (VZCARE)
In partnership with the University of Zambia (UNZA) and the Zambia Cancer Diseases Hospital (CDH), the Vanderbilt Institute for Global Health, the Vanderbilt Epidemiology Center and the Vanderbilt-Ingram Cancer Center received $1.3 million for a five-year training grant funded by the National Cancer Institute to support cancer epidemiology research in Zambia.
Vanderbilt-Nigeria Biostatistics Training Program (VN-BioStat)
Fellowship applications are open for this NIH collaborative research training grant focused on creating a cohort of highly skilled Nigerian biostatisticians with the capacity to lead and supervise high-level biostatistics activities for HIV research studies in West Africa. Focus includes hands-on biostatistics training. Trainees will take biostatistics courses, become members of a team of biostatisticians doing HIV research at Vanderbilt, and will be assigned to HIV research projects using data from Aminu Kano Teaching Hospital (AKTH).
Aima Ahonkhai receives grant to improve HIV care in Tennessee
The Office of Minority Health announced phase one winners of The HIV Challenge, a national competition seeking innovative approaches to reduce HIV-related stigma and increase prevention and treatment among minority communities. The HIV Challenge provides an opportunity for individuals and organizations to develop novel, innovative approaches for implementat
Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II (SPRING)
Strokes in sickle cell anemia (SCA), particularly in children living in Africa, are associated with significant morbidity and an increased risk of premature death. In the US, primary stroke prevention in children with SCA involves screening for elevated transcranial Doppler ultrasound (TCD) velocity coupled with regular blood transfusion therapy for those with elevated velocities. However, regular blood transfusion therapy is not feasible in Africa due to inadequate supply of safe blood and the reluctance of parents to accept regular blood transfusion therapy for their children.
Stroke Prevention in Young Adults With Sickle Cell Anemia (SPIYA)
Sickle cell disease (SCD) is the most common genetic disease, affecting about 25 million people worldwide. Approximately 150,000 Nigerian children are born each year with sickle cell disease (SCD), making it the country with the largest burden of SCD in the world. Recent advancements in care for children with SCA have translated into improved survival of children in both high and low-resource settings. However, more complications of SCD are seen in those who survive to adulthood.
TN Together: Opioid Abuse and Response
Tennessee anti-drug coalitions are working to reduce dependence on harmful and potentially lethal substances such as prescription drugs, alcohol, and tobacco. In partnership with the Hamilton County Coalition, researchers from Vanderbilt University Medical Center (VUMC) collect and analyze program demographics and outcomes. The Nu-Start program provides access to treatment and recovery services for individuals and families overcoming opioid dependency.
Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD)
This summer the National Institutes of Health (NIH) announced a new flagship initiative, the Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity, or AIM-AHEAD.
Applying Research for a Healthy Liberia
The University of Liberia College of Health Sciences is the leading educational institution for developing Liberia’s clinicians, researchers, health policymakers and innovators.
Higher Education Partnership for Innovation and Sustainable Biomedical Informatics Capacity in Kenya (PISBIC Kenya)
PI: Martin C. Were, M.D., M.S.
Immunogenetic predictors of active and incipient TB in HIV-negative and -positive close TB contacts
Principal Investigators: Timothy Sterling, MD Bruno Andrade Thomas Hawn
Aminu Kano Teaching Hospital-Bayero University Kano-Vanderbilt: Developing Future Leaders in Child Neurology and Epilepsy Research (ABV)
The Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL)
The West African Ebola outbreak of 2014-2015 exposed the fragility of Sierra Leone’s health system and highlighted the need for further investments to ensure its future capability of responding to a disease outbreak of this magnitude.
Etiology of Persistent Microalbuminuria in Nigeria
The Vanderbilt Institute for Global Health (VIGH) and Aminu Kano Teaching Hospital (AKTH) in Kano, Nigeria have received a federal grant to study the factors associated with microalbuminuria among participants in an ongoing clinical trial of genetically at-risk HIV-positive adult Nigerians. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) grant will provide $2.2 million over the next four years.
Bridging the Childhood Epilepsy Treatment Gap in Africa (BRIDGE)
Principal Investigator: Edwin Trevathan, MD, MPH
The Risk Of HIV Acquisition Among Traditional Healers In South Africa: Implementing Novel Strategies To Improve Protective Behavior
Traditional healers, community-based partners with the national health system of South Africa, are exposed to patient blood an average of 1,500 times during their careers due to the practice of delivering herbal remedies via herbs rubbed into dozens of sub-cutaneous cuts. The purpose of this proposal is to compare two implementation strategies to increase consistent use of PPE: (1) a health care worker provided training program followed by 3 educational outreach and coaching visits at the healer's place of practice vs.
An interactive, narrative intervention to address the mental health treatment gap among young people living with HIV in Nigeria
Young people living with HIV (Y-PLWH) have poor adherence to antiretroviral therapy and engagement in HIV care, making HIV the leading cause of death for African adolescents. Depression and psychological distress are much more common among Y-PLWH than in the general population, and are associated with significantly worse adherence to care and treatment when compared to Y-PLWH without these co-morbid conditions. Thus, untreated depression and severe psychological distress are important contributors to poor HIV outcomes in this population.
HIV Mobility and Engagement in Care in TN
The project connects Vanderbilt researchers across disciplines in order to understand how often people living with HIV move within or outside of the state, and if this mobility is associated with HIV outcomes.
CareConekta: study protocol for a randomized controlled trial of a mobile health intervention to improve engagement in postpartum HIV care in South Africa
South Africa has more HIV/AIDS patients than any other country and is home to the world’s largest antiretroviral program. According to the World Bank, as of 2018 the prevalence of HIV among South Africans ages 15 to 49 was 20.4%. Nearly one in three pregnant women attending antenatal care in South Africa is living with HIV. As South Africans with HIV move around the country, there is a risk they will disengage from the health care system or otherwise become lost to follow-up care.
Cure Sickle Cell Initiative Data Coordinating Center
Project Details: NIH Reporter
Mobile Health and Treat (mHAT) for Malaria Elimination
Principal Investigator(s): Martin Were, M.D., M.S. David Wright, Ph.D.
Liberia IRB Practicum and Workshop Series: Ethics Supplement
Building on the partnership with University of Liberia, College of Health Sciences (ULCHS), the Vanderbilt Institute for Global Health (VIGH) will develop a develop a one-year research ethics education program for members of four institutional review boards (IRBs) in Monrovia, Liberia. Research education and training activities will adapt to the Liberian context from the well-established Collaborative Research Ethics Education (Formação Colaborativa em Etica na Pesquisa, FoCEP) Program for Mozambique.
The South African National HIV Pregnancy Cohort: evaluating continuity of care among women living with HIV
Project Details: NIH Reporter
Predictors of treatment toxicity, failure, and relapse in HIV-related tuberculosis "RePORT-Brazil"
Principal Investigator(s):Timothy R. Sterling, M.D. Valeria Cavalcanti Rolla, M.D., Ph.D.
Traditional Healer-initiated HIV Counseling and Testing in Rural South Africa
In South Africa, HIV testing has been undermined by HIV stigma, distrust in the allopathic health system, a preference for traditional medicine, and distance to the health facility. South Africa has made progress towards their 90-90-90 goals, yet a substantial proportion of the population do not test regularly; only 33.9% of adults in rural Mpumalanga (our study site) underwent HIV testing in the past year.
Implementation of Rapid HIV Testing and Linkage to HIV Treatment or Prevention Among Vulnerable Populations in Tennessee
Human Immunodeficiency Virus (HIV) infection remains a significant public health problem in the United States (US). It is estimated that almost 15% of the 1.17 million people living with HIV (PLWH) in the US are unaware of their HIV status. And despite the existence of highly effective HIV treatment (antiretroviral therapy, ART), only 65% of people living with diagnosed HIV have achieved viral suppression. Similarly, among HIV-negative people eligible for PrEP, only 18% have used PrEP.
Examining antibody response to SARS-CoV-2 in Sierra Leone
Excerpt from the article Fogarty awards $3.3M in COVID-19 supplements to support research, training published in Global Health Matters by the Fogarty International Center:
Partnerships for Enhanced Engagement in Research Liberia (PEER/Liberia) Consortium
Principal Investigator(s): Bonnie Miller, M.D.Troy Moon, M.D. M.P.H.Marie Martin, M.Ed., Ph.D.
Childhood Status Epilepticus and Epilepsy Determinants of Outcome (SEED)
Status epilepticus (SE) is the most common serious neurological emergency among children worldwide. In the low- and middle-income countries (LMICs) of sub-Saharan Africa, the burden of childhood SE-associated mortality and morbidity appears to be especially high. However, the phenotypes of childhood SE, clinical predictors of SE-associated mortality and of SE-associated neurodevelopmental morbidity, and genomic predictors of SE, SE-associated mortality and neurodevelopmental morbidity have not been well-characterized in this region.
Partners-based HIV Treatment for Sero-concordant Couples attending Antenatal Care
Principal Investigator(s): Carolyn Audet, Ph.D.
Bridging the Childhood Epilepsy Treatment Gap in Northern Nigeria (BRIDGE)
Principal Investigator(s): Muktar Aliyu, M.D., M.P.H., Dr.P.H.Edwin Trevathan, M.D., M.P.H.
UNZA-Vanderbilt Partnership for HIV-NCD Research (UVP-2)
The UNZA-Vanderbilt Training Partnership for HIV-Nutrition-Metabolic Research (UVP-1) and the UNZA-Vanderbilt Partnership for HIV-NCD Research (UVP-2) continue a longstanding training collaboration between the University of Zambia School of Medicine/University Teaching Hospital (UNZA/UTH), Vanderbilt University (VU) and the Vanderbilt Institute for Global Health (VIGH).
Optimal Management of HIV Infected Adults at Risk for Kidney Disease in Nigeria
Principal Investigator(s): Muktar Aliyu, M.D., M.P.H., Dr.P.H.William Wester, M.D., M.P.H.
Vanderbilt Institute for Research Development and Ethics (VIRDE)
VIRDE is an annual intensive research training program designed to facilitate trainee research productivity in low- and middle-income countries (LMICs). This month-long program is intended to bolster and further develop the skill sets necessary for conducting responsible human subjects’ research and developing a grant proposal for submission. Attendees participate in a series of grant writing, research ethics/scientific integrity, and career development seminars and workshops.
Population mobility and retention in HIV care among postpartum women in South Africa
Principal Investigator(s): Kate Clouse, Ph.D., M.P.H.
Improving Perioperative Anesthesia Care and Training in Africa (ImPACT Africa)
The Improving Perioperative Anesthesia Care and Training in Africa (ImPACT Africa) program addresses the critical need for safe surgery by training local anesthesia providers and building educational capacity of local institutions. Vanderbilt Institute for Global Health (VIGH) faculty members, Marie Martin and Elizabeth Rose, along with other VIGH staff and student collaborators, have partnered with ImPACT Africa leaders to provide education consulting and develop new courses.
Clinical and genetic risk factors associated with adverse long-term health outcomes after curative therapies in individuals with sickle cell disease
Management of severe acute malnutrition in children with sickle cell disease greater than 5 years of age living in northern Nigeria
Project Details: NIH Reporter Abstract Text
PeerNaija: A Mobile Health Platform
The scale-up of global antiretroviral therapy (ART) represents an unparalleled global health success story, leading to impressive overall reductions in HIV-related morbidity and mortality. However, adolescents and young adults (AYA), especially those in Sub-Saharan Africa, have largely been left out of this story. While AIDS-related deaths declined by 30% for adults from 2005-2012, they increased by 50% among AYA over the same period, making AIDS the leading cause of death among African youth. AYA living with HIV perform poorly across the entire care continuum.
Vanderbilt-Nigeria Building Research Capacity in HIV/Non-communicable Diseases (V-BRCH)
The Vanderbilt-Nigeria Building Research Capacity in HIV/Non-communicable Diseases (V-BRCH) Program builds capacity of Nigerian investigators to successfully initiate and implement high-quality clinical trials in HIV-associated non-communicable diseases.
Avante: Towards Epidemic Control
Principal Investigator(s):William Wester, M.D., M.P.H.