Lawrence S. Gaines, Ph.D., Associate Professor of Psychiatry and Medicine, will soon be published in the American Journal of Gastroenterology. His paper is titled "Association between affective-cognitive symptoms of depression and exacerbation of Crohn's Disease." Affective-cognitive symptoms of depression predicted subsequent Crohn's disease activity and hospitalization rate, suggesting a temporal relationship. Crohn's disease activity is greater with baseline higher levels of affective-cognitive symptoms, suggesting a dose-response relationship. Symptom dimensions of depression maybe important in understanding the association of depression and Crohn's disease activity.