Prevention of Stroke in Children with Sickle Cell Anemia in Nigeria: A task shifting community hospital approach

September 23, 2020

Stroke is a devastating complication of sickle cell anemia (SCA) occurring in approximately 11% of children affected with the disease in resource-limited countries, compared to 1% in high-income countries. Nigeria bears 50% of childhood SCA's global burden, and stroke is a frequent complication leading to increased death and disability.

Moderate fixed‐dose hydroxyurea for primary prevention of strokes in Nigerian children with sickle cell disease: Final results of the SPIN trial

Gaby Harder
September 22, 2020

Sickle cell disease (SCD), an inherited blood disorder, is prevalent throughout sub-Saharan Africa. Approximately 240,000 children are born with SCD each year across the continent of Africa, and up to 70% of those infants born with sickle cell disease die before the age of five. 

VIGH awarded $3 million for building research capacity in Nigeria and Mozambique

June 11, 2020

Vanderbilt Institute for Global Health (VIGH) has received a new research training grant and a renewal for an existing training program from the Fogarty International Center (FIC) of the National Institutes of Health (NIH) to build HIV-focused research capacity with key partners in Nigeria and Mozambique. One of the $1.5 million grants will establish The Vanderbilt-Nigeria Building Research Capacity in HIV/Non-communicable Diseases (V-BRCH) Program to build capacity of Nigerian investigators to successfully initiate and implement high-quality clinical trials in HIV-associated non-communicable diseases.

VIGH study seeks to expand epilepsy care efforts in Africa

Holly Fletcher
October 14, 2019

The Vanderbilt Institute for Global Health, with Aminu Kano Teaching Hospital, will conduct a 60-site cluster randomized clinical trial in three cities in northern Nigeria to determine the efficacy of shifting childhood epilepsy care to epilepsy-trained community health extension workers with a five-year $5.9 million federal grant, “Bridging the Childhood Epilepsy Treatment Gap in Africa (BRIDGE),” from National Institute of Neurological Disorders and Stroke of the National Institutes of Health. Edwin Trevathan, M.D., M.P.H., Amos Christie Chair in Global Health, Professor of Pediatrics and

Science and PBS report on three places where "ending AIDS" is a distant hope

In 2016, Nigeria accounted for 37,000 of the world's 160,000 new cases of babies born with HIV. The most populous country in Africa, Nigeria does have an exceptionally large HIV-infected population of 3.2 million people. In other countries, however, rates of mother-to-child transmission of HIV have plummeted, even in far poorer countries. Mother-to-child transmission is only one part of Nigeria’s HIV epidemic.

VIGH Hosts Program for Strengthening Clinical Trial Regulation Capacity

June 7, 2018

This week, VIGH hosted visitors from Nigeria's National Agency for Food and Drug Administration Control (NAFDAC) and the National Agency for the Control of AIDS (NACA) to attend the VIGH Transdisciplinary Program for Strengthening Clinical Trial Regulation Capacity. The goal of this program was to build capacity of NAFDAC and NACA staff for clinical trial regulation and oversight of clinical trial protocols. NAFDAC, Nigeria's local equivalent of the U.S.