Moderate fixed‐dose hydroxyurea for primary prevention of strokes in Nigerian children with sickle cell disease: Final results of the SPIN trial

Gaby Harder
September 22, 2020

Sickle cell disease (SCD), an inherited blood disorder, is prevalent throughout sub-Saharan Africa. Approximately 240,000 children are born with SCD each year across the continent of Africa, and up to 70% of those infants born with sickle cell disease die before the age of five. 

VIGH awarded $3 million for building research capacity in Nigeria and Mozambique

June 11, 2020

Vanderbilt Institute for Global Health (VIGH) has received a new research training grant and a renewal for an existing training program from the Fogarty International Center (FIC) of the National Institutes of Health (NIH) to build HIV-focused research capacity with key partners in Nigeria and Mozambique. One of the $1.5 million grants will establish The Vanderbilt-Nigeria Building Research Capacity in HIV/Non-communicable Diseases (V-BRCH) Program to build capacity of Nigerian investigators to successfully initiate and implement high-quality clinical trials in HIV-associated non-communicable diseases.

Dr. Aliyu co-authors global ranking of COVID-19-related mortality using novel Pandemic Efficiency Index (PEI)​​​​​​​

April 15, 2020

The world is currently witnessing a dramatic disruption of everyday life owing to the rapid progression of the coronavirus disease 2019 (COVID-19) pandemic. As the pandemic evolves, there is an urgent need to better understand its epidemiology, characterize its potential impact, and identify mitigatory strategies to avert pandemic-related mortality. There is a need for a tool or algorithm to evaluate the extent to which public health policy and/or economic preparedness measures are effectively averting COVID-19 related mortality. We present a simple and yet practical epidemiological tool, the Pandemic Efficiency Index (PEI), that can be utilized globally to test the relative efficiency of measures put in place to avert death resulting from COVID-19 infection. Using the PEI and current COVID-19-related mortality, we determined that so far Germany demonstrates the highest PEI (5.1) among countries with more than 5,000 recorded cases of the infection, indicating high quality measures instituted by the country to avert death during the pandemic. Italy and France currently have the lowest COVID-19-related PEIs. Epidemics and pandemics come and go, but local, national, and global abilities to determine the efficiency of their efforts in averting deaths is critical.

Science and PBS report on three places where "ending AIDS" is a distant hope

In 2016, Nigeria accounted for 37,000 of the world's 160,000 new cases of babies born with HIV. The most populous country in Africa, Nigeria does have an exceptionally large HIV-infected population of 3.2 million people. In other countries, however, rates of mother-to-child transmission of HIV have plummeted, even in far poorer countries. Mother-to-child transmission is only one part of Nigeria’s HIV epidemic.

Vanderbilt at CROI 2016

February 18, 2016
Posted in


 
 Vanderbilt faculty from across campus will have a strong presence at the 2016 Conference on Retroviruses and Opportunistic Infections (CROI). In particular, VIGH core faculty Muktar Aliyu M.D., M.P.H., Dr.P.H and Kate Clouse Ph.D., M.P.H. and VIGH affiliated faculty will be presenting their work on optimizing the PMTCT cascade. See more details about their work and other Vanderbilt researchers below: