Young people living with HIV (Y-PLWH) have poor adherence to antiretroviral therapy and engagement in HIV care, making HIV the leading cause of death for African adolescents. Depression and psychological distress are much more common among Y-PLWH than in the general population, and are associated with significantly worse adherence to care and treatment when compared to Y-PLWH without these co-morbid conditions. Thus, untreated depression and severe psychological distress are important contributors to poor HIV outcomes in this population.
Aminu Kano Teaching Hospital (AKTH) and Bayero University Kano (BUK) in Kano, Nigeria, and Vanderbilt Institute for Global Health (VIGH) have a long history of successful NIH-funded collaborations in childhood brain disorders. These three institutions are partnering on a new $1.2 million, five-year training program funded by the Fogarty International Center at the National Institutes of Health (NIH) under Fogarty’s Chronic, Non-Communicable Diseases and Disorders Across the Lifespan Training Program.
The Vanderbilt Institute for Global Health (VIGH) and Aminu Kano Teaching Hospital (AKTH) in Kano, Nigeria have received a federal grant to study the factors associated with microalbuminuria among participants in an ongoing clinical trial of genetically at-risk HIV-positive adult Nigerians. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) grant will provide $2.2 million over the next four years.
The Vanderbilt Institute for Global Health (VIGH) has received a new research grant from the National Institute of Neurological Disorders and Stroke and Fogarty International Center of the NIH to establish a large childhood status epilepticus (SE) cohort in northern Nigeria with key partners Aminu Kano Teaching Hospital (AKTH) and Bayero University, and with the Sydney Brenner Institute for Molecular Bioscience at the University of the Witwatersrand (Wits) in South Africa.
Stroke is a devastating complication of sickle cell anemia (SCA) occurring in approximately 11% of children affected with the disease in resource-limited countries, compared to 1% in high-income countries. Nigeria bears 50% of childhood SCA's global burden, and stroke is a frequent complication leading to increased death and disability.
A recent study co-authored by Dr. Muktar Aliyu, M.D., MPH, DrPH, professor of Health Policy and Medicine and associate director for research for VIGH, assessed the willingness of students at Bayero University in Nigeria to self-test for HIV. The World Health Organization (WHO) encourages the use of HIV self-testing, especially in areas such as West and Central Africa where 64% of people living with HIV are unaware of their status.
Vanderbilt Institute for Global Health (VIGH) has received a new research training grant and a renewal for an existing training program from the Fogarty International Center (FIC) of the National Institutes of Health (NIH) to build HIV-focused research capacity with key partners in Nigeria and Mozambique. One of the $1.5 million grants will establish The Vanderbilt-Nigeria Building Research Capacity in HIV/Non-communicable Diseases (V-BRCH) Program to build capacity of Nigerian investigators to successfully initiate and implement high-quality clinical trials in HIV-associated non-communicable diseases.
The Vanderbilt Institute for Global Health, with Aminu Kano Teaching Hospital, will conduct a 60-site cluster randomized clinical trial in three cities in northern Nigeria to determine the efficacy of shifting childhood epilepsy care to epilepsy-trained community health extension workers with a five-year $5.9 million federal grant, “Bridging the Childhood Epilepsy Treatment Gap in Africa (BRIDGE),” from National Institute of Neurological Disorders and Stroke of the National Institutes of Health. Edwin Trevathan, M.D., M.P.H., Amos Christie Chair in Global Health, Professor of Pediatrics and
In 2016, Nigeria accounted for 37,000 of the world's 160,000 new cases of babies born with HIV. The most populous country in Africa, Nigeria does have an exceptionally large HIV-infected population of 3.2 million people. In other countries, however, rates of mother-to-child transmission of HIV have plummeted, even in far poorer countries. Mother-to-child transmission is only one part of Nigeria’s HIV epidemic.
This week, VIGH hosted visitors from Nigeria's National Agency for Food and Drug Administration Control (NAFDAC) and the National Agency for the Control of AIDS (NACA) to attend the VIGH Transdisciplinary Program for Strengthening Clinical Trial Regulation Capacity. The goal of this program was to build capacity of NAFDAC and NACA staff for clinical trial regulation and oversight of clinical trial protocols. NAFDAC, Nigeria's local equivalent of the U.S.
Researchers at the Vanderbilt Institute for Global Health (VIGH) recently received a two-year, $895,072 grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health (NIH) to study whether an integrated, family-focused approach can prevent mother-to-child transmission of HIV—the AIDS virus—in Nigeria.