Researchers from Vanderbilt’s Division of Nephrology and Hypertension have identified an under-studied characteristic that may have a protective effect on end-stage kidney disease (ESKD) risk among vulnerable populations. The study, led by Devika Nair, MD, MSCI, assistant professor of Medicine within the Division of Nephrology and Hypertension, found that adults who self-identified as Black and reported high levels of spirituality had a statistically significant reduced risk for developing ESKD — independent of demographics, other psychosocial factors and lifestyle behaviors.
Scientists are just beginning to understand the impact of diet on the gut microbiome and how this interaction affects human health, but baselines must first be established to yield answers. The first large-scale, longitudinal study to evaluate this interaction among Chinese adults indicates that long-term healthy eating yields microbiome diversity and an abundance of fiber-fermenting bacteria.
Breast-conserving surgery (BCS) plus radiotherapy is the standard-of-care for women diagnosed with early-stage breast cancer. For women over age 70, however, radiotherapy after BCS is controversial, and U.S. National Comprehensive Cancer Network clinical practice guidelines recommend that it may be omitted.
The TAILORx study published last year offered good news for women with early-stage ER-positive breast cancer who scored at intermediate risk for recurrence according to a genetic assay test. The study indicated that chemotherapy after surgery provided little advantage in overall survival for these women, so they could forgo the treatment.
Six clinics across four U.S. states provided data for a newly validated clinical risk stratification model for lung cancer. The TREAT model (Thoracic Surgery, Research, Epidemiology, Diagnosis And Treatment) helps identify patients with suspicious lesions who are most likely to benefit from surgical biopsy. The aim is to mitigate unnecessary surgery for benign nodules and reduce delays for patients with early cancers.
In a review of 526,690 patients who underwent radical prostatectomy for localized prostate cancer, researchers from Vanderbilt University Medical Center found Black patients had significantly higher mortality rates compared to other racial and ethnic groups. Asian Americans and Pacific Islanders (AAPIs) had notably lower mortality rates than non-Hispanic whites. Hispanics had slightly lower rates than non-Hispanic whites – despite lower socioeconomic status and significant underinsurance.