In the News

Geographic Variation in Women’s Colorectal Cancer Survival

A first look into where early onset mortality spikes among U.S. women. Women with early onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence, according to a study published in Clinical and Translational Gastroenterology.

Study finds breast cancer recurrence score has different implications for men

The TAILORx study published last year offered good news for women with early-stage ER-positive breast cancer who scored at intermediate risk for recurrence according to a genetic assay test. The study indicated that chemotherapy after surgery provided little advantage in overall survival for these women, so they could forgo the treatment.

Making Sense of Lung Nodules: Is It Cancer?

Six clinics across four U.S. states provided data for a newly validated clinical risk stratification model for lung cancer. The TREAT model (Thoracic Surgery, Research, Epidemiology, Diagnosis And Treatment) helps identify patients with suspicious lesions who are most likely to benefit from surgical biopsy. The aim is to mitigate unnecessary surgery for benign nodules and reduce delays for patients with early cancers.

Racial Disparities in Post-prostatectomy Mortality

In a review of 526,690 patients who underwent radical prostatectomy for localized prostate cancer, researchers from Vanderbilt University Medical Center found Black patients had significantly higher mortality rates compared to other racial and ethnic groups. Asian Americans and Pacific Islanders (AAPIs) had notably lower mortality rates than non-Hispanic whites. Hispanics had slightly lower rates than non-Hispanic whites – despite lower socioeconomic status and significant underinsurance.

Meat intake and colorectal polyps

Conventional colorectal adenomas are the precursor lesions for most colorectal cancers. In addition to these adenomas, other colorectal polyps are detected during colonoscopy. Sessile serrated polyps (SSPs) represent an alternative pathway to carcinogenesis that may account for 20-30% of colorectal cancer. Because a diagnostic consensus for SSPs was not reached until 2010, few epidemiologic studies have evaluated risk factors for SSPs.

Atlas Initiative to Map Colorectal Adenoma Progression

Conventional colorectal adenomas are the precursor lesions for most colorectal cancers. In addition to these adenomas, other colorectal polyps are detected during colonoscopy. Sessile serrated polyps (SSPs) represent an alternative pathway to carcinogenesis that may account for 20-30% of colorectal cancer. Because a diagnostic consensus for SSPs was not reached until 2010, few epidemiologic studies have evaluated risk factors for SSPs.