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Atlas Initiative to Map Colorectal Adenoma Progression

Conventional colorectal adenomas are the precursor lesions for most colorectal cancers. In addition to these adenomas, other colorectal polyps are detected during colonoscopy. Sessile serrated polyps (SSPs) represent an alternative pathway to carcinogenesis that may account for 20-30% of colorectal cancer. Because a diagnostic consensus for SSPs was not reached until 2010, few epidemiologic studies have evaluated risk factors for SSPs.