Department of Psychiatry and Behavioral Sciences

Guzikowski NJ, Wang CS, Kavalali ET. Functional Nano-segregation of Distinct Forms of Neurotransmission. Adv Neurobiol. 2026; 48: 217-57. PMID: 41569487, DOI: 10.1007/978-3-032-12594-1_8, ISSN: 2190-5215.
Kavalali ET. Nano-organization of the Synapse: A Requisite Framework for Synaptic Signaling. Adv Neurobiol. 2026; 48: 1-9. PMID: 41569480, DOI: 10.1007/978-3-032-12594-1_1, ISSN: 2190-5215.
Zhang KJ, Monteggia LM, Kavalali ET. Impact of distinct neurotransmitter release modes on neuronal signaling. Mol Psychiatry [print-electronic]. 2026 Feb; 31(2): 1095-110. PMID: 41299061, PMCID: PMC12815690, PII: 10.1038/s41380-025-03373-7, DOI: 10.1038/s41380-025-03373-7, ISSN: 1476-5578.

Ma ZZ, Guzikowski NJ, Kim JW, Kavalali ET, Monteggia LM. Enhanced ERK activity extends ketamine's antidepressant effects by augmenting synaptic plasticity. Science [print-electronic]. 2025 May 5/8/2025; 388(6747): 646-55. PMID: 40339008, DOI: 10.1126/science.abb6748, ISSN: 1095-9203.
McCarthy CI, Zack Ma Z, Monteggia LM, Kavalali ET. Spontaneous glutamate release activates mGluR signaling to drive rapid antidepressant responses. Proc Natl Acad Sci U S A [print-electronic]. 2025 Sep 9/16/2025; 122(37): e2510642122. PMID: 40924453, PMCID: PMC12452896, DOI: 10.1073/pnas.2510642122, ISSN: 1091-6490.
Guzikowski NJ, Bagatelas ED, Shin OH, Khan YA, Esquivies L, Alten B, Brunger AT, Kavalali ET. Synaptobrevin-2 disease variants reveal spatial constraints within the presynaptic active zone. Proc Natl Acad Sci U S A [print-electronic]. 2025 Nov 11/4/2025; 122(44): e2507347122. PMID: 41166419, PMCID: PMC12595502, DOI: 10.1073/pnas.2507347122, ISSN: 1091-6490.
Houcek AJ, Uzay B, Ildefonso GV, Omokehinde T, Monteggia LM, Quaranta V, Linkous A, Kavalali ET. Small cell lung cancer induces synaptic scaling to alter neuronal excitability. Commun Biol. 2025 Nov 11/13/2025; 8(1): 1559. PMID: 41233487, PMCID: PMC12615715, PII: 10.1038/s42003-025-09006-7, DOI: 10.1038/s42003-025-09006-7, ISSN: 2399-3642.
Uzay B, Zhang KJ, Monteggia LM, Kavalali ET. Dopaminergic tone inhibits spontaneous glutamate release and augments homeostatic synaptic plasticity. Mol Psychiatry [print-electronic]. 2025 Dec 12/6/2025; PMID: 41353489, PII: 10.1038/s41380-025-03374-6, DOI: 10.1038/s41380-025-03374-6, ISSN: 1476-5578.

Guzikowski NJ, Kavalali ET. Synaptic vesicle pool heterogeneity drives an anomalous form of synaptic plasticity. Proc Natl Acad Sci U S A [print-electronic]. 2024 Mar 3/12/2024; 121(11): e2401734121. PMID: 38422062, PMCID: PMC10945817, DOI: 10.1073/pnas.2401734121, ISSN: 1091-6490.
Wang CS, McCarthy CI, Guzikowski NJ, Kavalali ET, Monteggia LM. Brain-derived neurotrophic factor scales presynaptic calcium transients to modulate excitatory neurotransmission. Proc Natl Acad Sci U S A [print-electronic]. 2024 Apr 4/23/2024; 121(17): e2303664121. PMID: 38621124, PMCID: PMC11047077, DOI: 10.1073/pnas.2303664121, ISSN: 1091-6490.
Houcek A, Ma ZZ, Trauterman B, Uzay B, Monteggia LM, Kavalali ET. CRISPR-Cas9 editing of synaptic genes in human embryonic stem cells for functional analysis in induced human neurons. STAR Protoc [print-electronic]. 2024 Jun 6/21/2024; 5(2): 103089. PMID: 38795356, PMCID: PMC11152723, PII: S2666-1667(24)00254-5, DOI: 10.1016/j.xpro.2024.103089, ISSN: 2666-1667.
McCarthy CI, Kavalali ET. Nano-organization of synaptic calcium signaling. Biochem Soc Trans. 2024 Jun 6/26/2024; 52(3): 1459-71. PMID: 38752834, PMCID: PMC11346461, PII: 234448, DOI: 10.1042/BST20231385, ISSN: 1470-8752.
Bagatelas ED, Kavalali ET. Chronic modulation of cAMP signaling elicits synaptic scaling irrespective of activity. IScience. 2024 Jul 7/19/2024; 27(7): 110176. PMID: 38989459, PMCID: PMC11233962, PII: S2589-0042(24)01401-9, DOI: 10.1016/j.isci.2024.110176, ISSN: 2589-0042.
Afuwape OAT, Chanaday NL, Kasap M, Monteggia LM, Kavalali ET. Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins. J Physiol [print-electronic]. 2024 Aug 8/14/2024; PMID: 39141823, PMCID: PMC11825889, DOI: 10.1113/JP286711, ISSN: 1469-7793.
Kavalali ET, Monteggia LM. Synaptic basis of rapid antidepressant action. Eur Arch Psychiatry Clin Neurosci [print-electronic]. 2024 Sep 9/29/2024; PMID: 39343821, PII: 10.1007/s00406-024-01898-6, DOI: 10.1007/s00406-024-01898-6, ISSN: 1433-8491.
Piazza MK, Kavalali ET, Monteggia LM. Ketamine induced synaptic plasticity operates independently of long-term potentiation. Neuropsychopharmacology [print-electronic]. 2024 Oct; 49(11): 1758-66. PMID: 38898206, PMCID: PMC11399243, PII: 10.1038/s41386-024-01895-2, DOI: 10.1038/s41386-024-01895-2, ISSN: 1740-634X.
Kim JW, Kleinfelter B, Kavalali ET, Monteggia LM. Distinct synaptic mechanisms drive the behavioral response to acute stress and rapid correction by ketamine. Neuropsychopharmacology [print-electronic]. 2024 Nov; 49(12): 1916-24. PMID: 38956176, PMCID: PMC11473657, PII: 10.1038/s41386-024-01908-0, DOI: 10.1038/s41386-024-01908-0, ISSN: 1740-634X.
Guzikowski NJ, Kavalali ET. Functional specificity of liquid-liquid phase separation at the synapse. Nat Commun. 2024 Nov 11/21/2024; 15(1): 10103. PMID: 39572583, PMCID: PMC11582584, PII: 10.1038/s41467-024-54423-7, DOI: 10.1038/s41467-024-54423-7, ISSN: 2041-1723.

Uzay B, Kavalali ET. Genetic disorders of neurotransmitter release machinery. Front Synaptic Neurosci. 2023; 15: 1148957. PMID: 37066095, PMCID: PMC10102358, DOI: 10.3389/fnsyn.2023.1148957, ISSN: 1663-3563.
Jaczynska K, Esquivies L, Pfuetzner RA, Alten B, Brewer KD, Zhou Q, Kavalali ET, Brunger AT, Rizo J. Analysis of tripartite Synaptotagmin-1-SNARE-complexin-1 complexes in solution. FEBS Open Bio [print-electronic]. 2023 Jan; 13(1): 26-50. PMID: 36305864, PMCID: PMC9811660, DOI: 10.1002/2211-5463.13503, ISSN: 2211-5463.
Uzay B, Houcek A, Ma ZZ, Konradi C, Monteggia LM, Kavalali ET. Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging. Cell Rep [print-electronic]. 2023 Jan 1/25/2023; 42(2): 112042. PMID: 36701235, PII: S2211-1247(23)00053-0, DOI: 10.1016/j.celrep.2023.112042, ISSN: 2211-1247.
Guzikowski NJ, Kavalali ET. Super-resolution imaging of synaptic scaffold proteins in rat hippocampal neurons. STAR Protoc [print-electronic]. 2023 Feb 2/2/2023; 4(1): 102080. PMID: 36853692, PMCID: PMC9932186, PII: S2666-1667(23)00038-2, DOI: 10.1016/j.xpro.2023.102080, ISSN: 2666-1667.
Kim JW, Suzuki K, Kavalali ET, Monteggia LM. Bridging rapid and sustained antidepressant effects of ketamine. Trends Mol Med [print-electronic]. 2023 May; 29(5): 364-75. PMID: 36907686, PMCID: PMC10101916, PII: S1471-4914(23)00035-7, DOI: 10.1016/j.molmed.2023.02.003, ISSN: 1471-499X.
Kavalali ET. Interrogating synaptic transmission at circadian time scales. J Physiol [print-electronic]. 2023 May; 601(10): 1697-8. PMID: 36994489, DOI: 10.1113/JP284668, ISSN: 1469-7793.
Krystal JH, Kavalali ET, Monteggia LM. Ketamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms. Neuropsychopharmacology [print-electronic]. 2023 Jul 7/24/2023; PMID: 37488280, PII: 10.1038/s41386-023-01629-w, DOI: 10.1038/s41386-023-01629-w, ISSN: 1740-634X.
Kim JW, Suzuki K, Kavalali ET, Monteggia LM. Ketamine: Mechanisms and Relevance to Treatment of Depression. Annu Rev Med [print-electronic]. 2023 Sep 9/20/2023; PMID: 37729028, DOI: 10.1146/annurev-med-051322-120608, ISSN: 1545-326X.

Wang CS, Kavalali ET, Monteggia LM. BDNF signaling in context: From synaptic regulation to psychiatric disorders. Cell [print-electronic]. 2022 Jan 1/6/2022; 185(1): 62-76. PMID: 34963057, PMCID: PMC8741740, PII: S0092-8674(21)01425-2, DOI: 10.1016/j.cell.2021.12.003, ISSN: 1097-4172.
Alten B, Guzikowski NJ, Zurawski Z, Hamm HE, Kavalali ET. Presynaptic mechanisms underlying GABA_B-receptor-mediated inhibition of spontaneous neurotransmitter release. Cell Rep. 2022 Jan 1/18/2022; 38(3): 110255. PMID: 35045279, PMCID: PMC8793855, PII: S2211-1247(21)01767-8, DOI: 10.1016/j.celrep.2021.110255, ISSN: 2211-1247.

Guzikowski NJ, Kavalali ET. Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission. Front Synaptic Neurosci. 2021; 13: 796498. PMID: 35002671, PMCID: PMC8727373, DOI: 10.3389/fnsyn.2021.796498, ISSN: 1663-3563.
Alten B, Zhou Q, Shin OH, Esquivies L, Lin PY, White KI, Sun R, Chung WK, Monteggia LM, Brunger AT, Kavalali ET. Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies. Neuron [print-electronic]. 2021 Jan 1/6/2021; 109(1): 59-72.e5. PMID: 33147442, PMCID: PMC7790958, PII: S0896-6273(20)30808-4, DOI: 10.1016/j.neuron.2020.10.012, ISSN: 1097-4199.
Chanaday NL, Nosyreva E, Shin OH, Zhang H, Aklan I, Atasoy D, Bezprozvanny I, Kavalali ET. Presynaptic store-operated Ca²⁺ entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress. Neuron [print-electronic]. 2021 Mar 3/4/2021; PMID: 33711258, PII: S0896-6273(21)00123-9, DOI: 10.1016/j.neuron.2021.02.023, ISSN: 1097-4199.
Vilcaes AA, Chanaday NL, Kavalali ET. Interneuronal exchange and functional integration of synaptobrevin via extracellular vesicles. Neuron [print-electronic]. 2021 Mar 3/17/2021; 109(6): 971-983.e5. PMID: 33513363, PMCID: PMC7979516, PII: S0896-6273(21)00007-6, DOI: 10.1016/j.neuron.2021.01.007, ISSN: 1097-4199.
Shin OH, Kavalali ET. Evolutionary diversity of the dual Ca²⁺ sensor system for neurotransmitter release. Cell Calcium [print-electronic]. 2021 Mar 3/26/2021; 96: 102402. PMID: 33813181, PII: S0143-4160(21)00056-7, DOI: 10.1016/j.ceca.2021.102402, ISSN: 1532-1991.
Kim JW, Herz J, Kavalali ET, Monteggia LM. A key requirement for synaptic Reelin signaling in ketamine-mediated behavioral and synaptic action. Proc Natl Acad Sci U S A. 2021 May 5/18/2021; 118(20): PMID: 33975959, PMCID: PMC8157952, PII: 2103079118, DOI: 10.1073/pnas.2103079118, ISSN: 1091-6490.
Kim JW, Autry AE, Na ES, Adachi M, Björkholm C, Kavalali ET, Monteggia LM. Sustained effects of rapidly acting antidepressants require BDNF-dependent MeCP2 phosphorylation. Nat Neurosci [print-electronic]. 2021 Aug; 24(8): 1100-9. PMID: 34183865, PMCID: PMC8338784, PII: 10.1038/s41593-021-00868-8, DOI: 10.1038/s41593-021-00868-8, ISSN: 1546-1726.
Horvath PM, Chanaday NL, Alten B, Kavalali ET, Monteggia LM. A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength. Cell Rep. 2021 Aug 8/3/2021; 36(5): 109467. PMID: 34348149, PMCID: PMC8371576, PII: S2211-1247(21)00890-1, DOI: 10.1016/j.celrep.2021.109467, ISSN: 2211-1247.
Lin PY, Ma ZZ, Mahgoub M, Kavalali ET, Monteggia LM. A synaptic locus for TrkB signaling underlying ketamine rapid antidepressant action. Cell Rep. 2021 Aug 8/17/2021; 36(7): 109513. PMID: 34407417, PMCID: PMC8404212, PII: S2211-1247(21)00943-8, DOI: 10.1016/j.celrep.2021.109513, ISSN: 2211-1247.
Chanaday NL, Kavalali ET. Synaptobrevin-2 dependent regulation of single synaptic vesicle endocytosis. Mol Biol Cell [print-electronic]. 2021 Sep 9/1/2021; 32(19): 1818-23. PMID: 34191540, DOI: 10.1091/mbc.E21-04-0213, ISSN: 1939-4586.
Suzuki K, Kim JW, Nosyreva E, Kavalali ET, Monteggia LM. Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action. Cell Rep. 2021 Nov 11/2/2021; 37(5): 109918. PMID: 34731624, PMCID: PMC8590465, PII: S2211-1247(21)01391-7, DOI: 10.1016/j.celrep.2021.109918, ISSN: 2211-1247.

Bezprozvanny I, Kavalali ET. Presynaptic endoplasmic reticulum and neurotransmission. Cell Calcium [print-electronic]. 2020 Jan; 85: 102133. PMID: 31812114, PII: S0143-4160(19)30202-7, DOI: 10.1016/j.ceca.2019.102133, ISSN: 1532-1991.
Chanaday NL, Kavalali ET. Is Ca²⁺ Essential for Synaptic Vesicle Endocytosis?. Trends Neurosci [print-electronic]. 2020 Feb; 43(2): 77-9. PMID: 31910996, PII: S0166-2236(19)30223-1, DOI: 10.1016/j.tins.2019.12.001, ISSN: 1878-108X.
Horvath PM, Piazza MK, Monteggia LM, Kavalali ET. Spontaneous and evoked neurotransmission are partially segregated at inhibitory synapses. Elife. 2020 May 5/13/2020; 9: PMID: 32401197, PMCID: PMC7250572, PII: 52852, DOI: 10.7554/eLife.52852, ISSN: 2050-084X.
Kavalali ET, Monteggia LM. Targeting Homeostatic Synaptic Plasticity for Treatment of Mood Disorders. Neuron. 2020 Jun 6/3/2020; 106(5): 715-26. PMID: 32497508, PII: S0896-6273(20)30361-5, DOI: 10.1016/j.neuron.2020.05.015, ISSN: 1097-4199.
Lin PY, Chanaday NL, Horvath PM, Ramirez DMO, Monteggia LM, Kavalali ET. VAMP4 maintains a Ca²⁺-sensitive pool of spontaneously recycling synaptic vesicles. J. Neurosci [print-electronic]. 2020 Jun 6/12/2020; PMID: 32532887, PII: JNEUROSCI.2386-19.2020, DOI: 10.1523/JNEUROSCI.2386-19.2020, ISSN: 1529-2401.
Simmons RL, Li H, Alten B, Santos MS, Jiang R, Paul B, Lalani SJ, Cortesi A, Parks K, Khandelwal N, Smith-Packard B, Phoong MA, Chez M, Fisher H, Scheuerle AE, Shinawi M, Hussain SA, Kavalali ET, Sherr EH, Voglmaier SM. Overcoming presynaptic effects of VAMP2 mutations with 4-aminopyridine treatment. Hum Mutat [print-electronic]. 2020 Nov; 41(11): 1999-2011. PMID: 32906212, DOI: 10.1002/humu.24109, ISSN: 1098-1004.

Kavalali ET. Neuronal Ca²⁺ signalling at rest and during spontaneous neurotransmission. J. Physiol. (Lond.) [print-electronic]. 2019 Feb 2/8/2019; PMID: 30735245, DOI: 10.1113/JP276541, ISSN: 1469-7793.
Hoerder-Suabedissen A, Korrell KV, Hayashi S, Jeans A, Ramirez DMO, Grant E, Christian HC, Kavalali ET, Wilson MC, Molnár Z. Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration. Cereb. Cortex. 2019 May 5/1/2019; 29(5): 2148-59. PMID: 29850799, PMCID: PMC6754517, PII: 5025424, DOI: 10.1093/cercor/bhy127, ISSN: 1460-2199.
Monteggia LM, Lin PY, Adachi M, Kavalali ET. Behavioral Analysis of SNAP-25 and Synaptobrevin-2 Haploinsufficiency in Mice. Neuroscience [print-electronic]. 2019 Nov 11/10/2019; 420: 129-35. PMID: 30144509, PMCID: PMC6387657, PII: S0306-4522(18)30559-1, DOI: 10.1016/j.neuroscience.2018.08.014, ISSN: 1873-7544.

Kavalali ET. Spontaneous neurotransmission: A form of neural communication comes of age. J. Neurosci. Res [print-electronic]. 2018 Mar; 96(3): 331-4. PMID: 29219198, PMCID: PMC5766395, DOI: 10.1002/jnr.24207, ISSN: 1097-4547.
Chanaday NL, Kavalali ET. Optical detection of three modes of endocytosis at hippocampal synapses. Elife. 2018 Apr 4/23/2018; 7: PMID: 29683423, PMCID: PMC5959719, PII: 36097, DOI: 10.7554/eLife.36097, ISSN: 2050-084X.
Liu P, Khvotchev M, Li YC, Chanaday NL, Kavalali ET. Copine-6 Binds to SNAREs and Selectively Suppresses Spontaneous Neurotransmission. J. Neurosci [print-electronic]. 2018 Jun 6/27/2018; 38(26): 5888-99. PMID: 29802203, PMCID: PMC6021993, PII: JNEUROSCI.0461-18.2018, DOI: 10.1523/JNEUROSCI.0461-18.2018, ISSN: 1529-2401.
Chanaday NL, Kavalali ET. Presynaptic origins of distinct modes of neurotransmitter release. Curr. Opin. Neurobiol [print-electronic]. 2018 Aug; 51: 119-26. PMID: 29597140, PMCID: PMC6066415, PII: S0959-4388(17)30286-6, DOI: 10.1016/j.conb.2018.03.005, ISSN: 1873-6882.
Lin PY, Kavalali ET, Monteggia LM. Genetic Dissection of Presynaptic and Postsynaptic BDNF-TrkB Signaling in Synaptic Efficacy of CA3-CA1 Synapses. Cell Rep. 2018 Aug 8/7/2018; 24(6): 1550-61. PMID: 30089265, PII: S2211-1247(18)31110-0, DOI: 10.1016/j.celrep.2018.07.020, ISSN: 2211-1247.
Chanaday NL, Kavalali ET. Time course and temperature dependence of synaptic vesicle endocytosis. FEBS Lett [print-electronic]. 2018 Nov; 592(21): 3606-14. PMID: 30311950, DOI: 10.1002/1873-3468.13268, ISSN: 1873-3468.

Li YC, Chanaday NL, Xu W, Kavalali ET. Synaptotagmin-1- and Synaptotagmin-7-Dependent Fusion Mechanisms Target Synaptic Vesicles to Kinetically Distinct Endocytic Pathways. Neuron [print-electronic]. 2017 Feb 2/8/2017; 93(3): 616-631.e3. PMID: 28111077, PMCID: PMC5300960, PII: S0896-6273(16)30949-7, DOI: 10.1016/j.neuron.2016.12.010, ISSN: 1097-4199.
Crawford DC, Ramirez DM, Trauterman B, Monteggia LM, Kavalali ET. Selective molecular impairment of spontaneous neurotransmission modulates synaptic efficacy. Nat Commun. 2017 Feb 2/10/2017; 8: 14436. PMID: 28186166, PMCID: PMC5311059, PII: ncomms14436, DOI: 10.1038/ncomms14436, ISSN: 2041-1723.
Li YC, Kavalali ET. Synaptic Vesicle-Recycling Machinery Components as Potential Therapeutic Targets. Pharmacol. Rev. 2017 Apr; 69(2): 141-60. PMID: 28265000, PMCID: PMC5394918, PII: 69/2/141, DOI: 10.1124/pr.116.013342, ISSN: 1521-0081.
Suzuki K, Nosyreva E, Hunt KW, Kavalali ET, Monteggia LM. Effects of a ketamine metabolite on synaptic NMDAR function. Nature. 2017 Jun 6/21/2017; 546(7659): E1-E3. PMID: 28640258, PII: nature22084, DOI: 10.1038/nature22084, ISSN: 1476-4687.
Ramirez DMO, Crawford DC, Chanaday NL, Trauterman B, Monteggia LM, Kavalali ET. Loss of Doc2-Dependent Spontaneous Neurotransmission Augments Glutamatergic Synaptic Strength. J. Neurosci [print-electronic]. 2017 Jun 6/28/2017; 37(26): 6224-30. PMID: 28539418, PMCID: PMC5490061, PII: JNEUROSCI.0418-17.2017, DOI: 10.1523/JNEUROSCI.0418-17.2017, ISSN: 1529-2401.

Reese AL, Kavalali ET. Single synapse evaluation of the postsynaptic NMDA receptors targeted by evoked and spontaneous neurotransmission. Elife. 2016 Nov 11/24/2016; 5: PMID: 27882871, PMCID: PMC5148599, DOI: 10.7554/eLife.21170, ISSN: 2050-084X.

Kavalali ET. The mechanisms and functions of spontaneous neurotransmitter release. Nat. Rev. Neurosci. 2015 Jan; 16(1): 5-16. PMID: 25524119, PII: nrn3875, DOI: 10.1038/nrn3875, ISSN: 1471-0048.
Reese AL, Kavalali ET. Spontaneous neurotransmission signals through store-driven Ca(2+) transients to maintain synaptic homeostasis. Elife. 2015 Jul 7/24/2015; 4: PMID: 26208337, PMCID: PMC4534843, DOI: 10.7554/eLife.09262, ISSN: 2050-084X.

Kavalali ET, Jorgensen EM. Visualizing presynaptic function. Nat. Neurosci [print-electronic]. 2014 Jan; 17(1): 10-6. PMID: 24369372, PII: nn.3578, DOI: 10.1038/nn.3578, ISSN: 1546-1726.
Gideons ES, Kavalali ET, Monteggia LM. Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2014 Jun 6/10/2014; 111(23): 8649-54. PMID: 24912158, PMCID: PMC4060670, PII: 1323920111, DOI: 10.1073/pnas.1323920111, ISSN: 1091-6490.
Leitz J, Kavalali ET. Fast retrieval and autonomous regulation of single spontaneously recycling synaptic vesicles. Elife. 2014 Nov 11/21/2014; 3: e03658. PMID: 25415052, PMCID: PMC4270043, DOI: 10.7554/eLife.03658, ISSN: 2050-084X.

Nosyreva E, Szabla K, Autry AE, Ryazanov AG, Monteggia LM, Kavalali ET. Acute suppression of spontaneous neurotransmission drives synaptic potentiation. J. Neurosci. 2013 Apr 4/17/2013; 33(16): 6990-7002. PMID: 23595756, PMCID: PMC3661220, PII: 33/16/6990, DOI: 10.1523/JNEUROSCI.4998-12.2013, ISSN: 1529-2401.
Bal M, Leitz J, Reese AL, Ramirez DM, Durakoglugil M, Herz J, Monteggia LM, Kavalali ET. Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission. Neuron [print-electronic]. 2013 Nov 11/20/2013; 80(4): 934-46. PMID: 24210904, PMCID: PMC3840105, PII: S0896-6273(13)00758-7, DOI: 10.1016/j.neuron.2013.08.024, ISSN: 1097-4199.

Kavalali ET, Monteggia LM. Synaptic mechanisms underlying rapid antidepressant action of ketamine. Am J Psychiatry. 2012 Nov; 169(11): 1150-6. PMID: 23534055, DOI: 10.1176/appi.ajp.2012.12040531, ISSN: 1535-7228.

Ege Kavalali, Ph.D.

Selected Publications