Department of Psychiatry and Behavioral Sciences

Mukherjee D, Ignatowska-Jankowska BM, Itskovits E, Gonzales BJ, Turm H, Izakson L, Haritan D, Bleistein N, Cohen C, Amit I, Shay T, Grueter B, Zaslaver A, Citri A. Salient experiences are represented by unique transcriptional signatures in the mouse brain. Elife. 2018 Feb 2/7/2018; 7: PMID: 29412137, PMCID: PMC5862526, PII: 31220, DOI: 10.7554/eLife.31220, ISSN: 2050-084X.
Reddy IA, Smith NK, Erreger K, Ghose D, Saunders C, Foster DJ, Turner B, Poe A, Albaugh VL, McGuinness O, Hackett TA, Grueter BA, Abumrad NN, Flynn CR, Galli A. Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward. PLoS Biol. 2018 Jul; 16(7): e2006682. PMID: 30048457, PMCID: PMC6061973, PII: pbio.2006682, DOI: 10.1371/journal.pbio.2006682, ISSN: 1545-7885.
Turner BD, Rook JM, Lindsley CW, Conn PJ, Grueter BA. MGlu₁ and mGlu₅ modulate distinct excitatory inputs to the nucleus accumbens shell. Neuropsychopharmacology [print-electronic]. 2018 Sep; 43(10): 2075-82. PMID: 29654259, PMCID: PMC6097986, PII: 10.1038/s41386-018-0049-1, DOI: 10.1038/s41386-018-0049-1, ISSN: 1740-634X.
Turner BD, Kashima DT, Manz KM, Grueter CA, Grueter BA. Synaptic Plasticity in the Nucleus Accumbens: Lessons Learned from Experience. ACS Chem Neurosci [print-electronic]. 2018 Sep 9/19/2018; 9(9): 2114-26. PMID: 29280617, PMCID: PMC6508969, DOI: 10.1021/acschemneuro.7b00420, ISSN: 1948-7193.
Joffe ME, Turner BD, Delpire E, Grueter BA. Genetic loss of GluN2B in D1-expressing cell types enhances long-term cocaine reward and potentiation of thalamo-accumbens synapses. Neuropsychopharmacology [print-electronic]. 2018 Nov; 43(12): 2383-9. PMID: 29982266, PMCID: PMC6180117, PII: 10.1038/s41386-018-0131-8, DOI: 10.1038/s41386-018-0131-8, ISSN: 1740-634X.

Joffe ME, Vitter SR, Grueter BA. GluN1 deletions in D1- and A2A-expressing cell types reveal distinct modes of behavioral regulation. Neuropharmacology [print-electronic]. 2017 Jan; 112(Pt A): 172-80. PMID: 27012890, PMCID: PMC5031515, PII: S0028-3908(16)30098-3, DOI: 10.1016/j.neuropharm.2016.03.026, ISSN: 1873-7064.
Ghoshal A, Moran SP, Dickerson JW, Joffe ME, Grueter BA, Xiang Z, Lindsley CW, Rook JM, Conn PJ. Role of mGlu5 Receptors and Inhibitory Neurotransmission in M1 Dependent Muscarinic LTD in the Prefrontal Cortex: Implications in Schizophrenia. ACS Chem Neurosci [print-electronic]. 2017 Aug 8/9/2017; PMID: 28679049, DOI: 10.1021/acschemneuro.7b00167, ISSN: 1948-7193.
Kashima DT, Grueter BA. Toll-like receptor 4 deficiency alters nucleus accumbens synaptic physiology and drug reward behavior. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2017 Aug 8/15/2017; 114(33): 8865-70. PMID: 28760987, PII: 1705974114, DOI: 10.1073/pnas.1705974114, ISSN: 1091-6490.

Báldi R, Ghosh D, Grueter BA, Patel S. Electrophysiological Measurement of Cannabinoid-Mediated Synaptic Modulation in Acute Mouse Brain Slices. Curr Protoc Neurosci. 2016 Apr 4/8/2016; 75: 6.29.1-6.29.19. PMID: 27063786, PMCID: PMC4866814, DOI: 10.1002/cpns.8, ISSN: 1934-8576.
Joffe ME, Grueter BA. Cocaine Experience Enhances Thalamo-Accumbens N-Methyl-D-Aspartate Receptor Function. Biol. Psychiatry [print-electronic]. 2016 Nov 11/1/2016; 80(9): 671-81. PMID: 27209241, PMCID: PMC5050082, PII: S0006-3223(16)32265-X, DOI: 10.1016/j.biopsych.2016.04.002, ISSN: 1873-2402.

Klar R, Walker AG, Ghose D, Grueter BA, Engers DW, Hopkins CR, Lindsley CW, Xiang Z, Conn PJ, Niswender CM. Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus. J. Neurosci. 2015 May 5/13/2015; 35(19): 7600-15. PMID: 25972184, PMCID: PMC4429158, PII: 35/19/7600, DOI: 10.1523/JNEUROSCI.4543-14.2015, ISSN: 1529-2401.

Joffe ME, Grueter CA, Grueter BA. Biological substrates of addiction. Wiley Interdiscip Rev Cogn Sci [print-electronic]. 2014 Mar; 5(2): 151-71. PMID: 24999377, PMCID: PMC4078878, DOI: 10.1002/wcs.1273, ISSN: 1939-5086.
Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dolen G, Bader PL, Grueter BA, Goold C, Fisher E, Clifford K, Rengarajan P, Kalikhman D, Loureiro D, Saw NL, Zhengqui Z, Miller MA, Lerch JP, Henkelman M, Shamloo M, Malenka RC, Crawley JN, Dolmetsch RE. Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. Cell Rep [print-electronic]. 2014 May 5/22/2014; 7(4): 1077-92. PMID: 24794428, PMCID: PMC4251471, PII: S2211-1247(14)00214-9, DOI: 10.1016/j.celrep.2014.03.036, ISSN: 2211-1247.

Grueter BA, Robison AJ, Neve RL, Nestler EJ, Malenka RC. ¿FosB differentially modulates nucleus accumbens direct and indirect pathway function. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2013 Jan 1/29/2013; 110(5): 1923-8. PMID: 23319622, PMCID: PMC3562792, PII: 1221742110, DOI: 10.1073/pnas.1221742110, ISSN: 1091-6490.
Xu P, Grueter BA, Britt JK, McDaniel L, Huntington PJ, Hodge R, Tran S, Mason BL, Lee C, Vong L, Lowell BB, Malenka RC, Lutter M, Pieper AA. Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2013 Jun 6/25/2013; 110(26): 10759-64. PMID: 23754400, PMCID: PMC3696762, PII: 1308195110, DOI: 10.1073/pnas.1308195110, ISSN: 1091-6490.

Daadi MM, Grueter BA, Malenka RC, Redmond DE, Steinberg GK. Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease. PLoS ONE [print-electronic]. 2012; 7(7): e41120. PMID: 22815935, PMCID: PMC3398927, PII: PONE-D-12-03793, DOI: 10.1371/journal.pone.0041120, ISSN: 1932-6203.
Grueter BA, Rothwell PE, Malenka RC. Integrating synaptic plasticity and striatal circuit function in addiction. Curr. Opin. Neurobiol [print-electronic]. 2012 Jun; 22(3): 545-51. PMID: 22000687, PMCID: PMC3276730, PII: S0959-4388(11)00153-X, DOI: 10.1016/j.conb.2011.09.009, ISSN: 1873-6882.
Nelson AB, Hang GB, Grueter BA, Pascoli V, Luscher C, Malenka RC, Kreitzer AC. A comparison of striatal-dependent behaviors in wild-type and hemizygous Drd1a and Drd2 BAC transgenic mice. J. Neurosci. 2012 Jul 7/4/2012; 32(27): 9119-23. PMID: 22764221, PMCID: PMC3420343, PII: 32/27/9119, DOI: 10.1523/JNEUROSCI.0224-12.2012, ISSN: 1529-2401.
Lim BK, Huang KW, Grueter BA, Rothwell PE, Malenka RC. Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens. Nature. 2012 Jul 7/11/2012; 487(7406): 183-9. PMID: 22785313, PMCID: PMC3397405, PII: nature11160, DOI: 10.1038/nature11160, ISSN: 1476-4687.

Gosnell HB, Silberman Y, Grueter BA, Duvoisin RM, Raber J, Winder DG. MGluR8 modulates excitatory transmission in the bed nucleus of the stria terminalis in a stress-dependent manner. Neuropsychopharmacology [print-electronic]. 2011 Jul; 36(8): 1599-607. PMID: 21451497, PMCID: PMC3138653, PII: npp201140, DOI: 10.1038/npp.2011.40, ISSN: 1740-634X.

McElligott ZA, Klug JR, Nobis WP, Patel S, Grueter BA, Kash TL, Winder DG. Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2010 Feb 2/2/2010; 107(5): 2271-6. PMID: 20133871, PMCID: PMC2836642, PII: 0905568107, DOI: 10.1073/pnas.0905568107, ISSN: 1091-6490.
Grueter BA, Brasnjo G, Malenka RC. Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens. Nat. Neurosci [print-electronic]. 2010 Dec; 13(12): 1519-25. PMID: 21076424, PMCID: PMC3092590, PII: nn.2685, DOI: 10.1038/nn.2685, ISSN: 1546-1726.

Daadi MM, Lee SH, Arac A, Grueter BA, Bhatnagar R, Maag AL, Schaar B, Malenka RC, Palmer TD, Steinberg GK. Functional engraftment of the medial ganglionic eminence cells in experimental stroke model. Cell Transplant [print-electronic]. 2009; 18(7): 815-26. PMID: 19500468, PII: CT-2009, DOI: 10.3727/096368909X470829, ISSN: 1555-3892.
Daadi MM, Li Z, Arac A, Grueter BA, Sofilos M, Malenka RC, Wu JC, Steinberg GK. Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain. Mol. Ther [print-electronic]. 2009 Jul; 17(7): 1282-91. PMID: 19436269, PMCID: PMC2835224, PII: S1525-0016(16)31840-8, DOI: 10.1038/mt.2009.104, ISSN: 1525-0024.

Grueter BA, McElligott ZA, Robison AJ, Mathews GC, Winder DG. In vivo metabotropic glutamate receptor 5 (mGluR5) antagonism prevents cocaine-induced disruption of postsynaptically maintained mGluR5-dependent long-term depression. J. Neurosci. 2008 Sep 9/10/2008; 28(37): 9261-70. PMID: 18784306, PMCID: PMC2562219, PII: 28/37/9261, DOI: 10.1523/JNEUROSCI.2886-08.2008, ISSN: 1529-2401.

Grueter BA, McElligott ZA, Winder DG. Group I mGluRs and long-term depression: potential roles in addiction?. Mol. Neurobiol [print-electronic]. 2007 Dec; 36(3): 232-44. PMID: 17955198, DOI: 10.1007/s12035-007-0037-7, ISSN: 0893-7648.

Grueter BA, Gosnell HB, Olsen CM, Schramm-Sapyta NL, Nekrasova T, Landreth GE, Winder DG. Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration. J. Neurosci. 2006 Mar 3/22/2006; 26(12): 3210-9. PMID: 16554472, PII: 26/12/3210, DOI: 10.1523/JNEUROSCI.0170-06.2006, ISSN: 1529-2401.

Grueter BA, Winder DG. Group II and III metabotropic glutamate receptors suppress excitatory synaptic transmission in the dorsolateral bed nucleus of the stria terminalis. Neuropsychopharmacology. 2005 Jul; 30(7): 1302-11. PMID: 15812571, PII: 1300672, DOI: 10.1038/sj.npp.1300672, ISSN: 0893-133X.

Weitlauf C, Egli RE, Grueter BA, Winder DG. High-frequency stimulation induces ethanol-sensitive long-term potentiation at glutamatergic synapses in the dorsolateral bed nucleus of the stria terminalis. J. Neurosci. 2004 Jun 6/23/2004; 24(25): 5741-7. PMID: 15215296, PII: 24/25/5741, DOI: 10.1523/JNEUROSCI.1181-04.2004, ISSN: 1529-2401.

Brad Grueter, Ph.D.

Selected Publications