Hollender Lecture in Geriatric Psychiatry | Krista L. Lanctôt, PhD

Hollender Lecture AY24

"Dementia-related apathy: Recent advances in diagnosis and treatment"


About the Speaker:

Krista L. Lanctôt, PhD
Bernick Chair in Geriatric Psychopharmacology;
Senior Scientist, Sunnybrook Research Institute;
Professor of Psychiatry and Pharmacology,
Vice Chair, Basic and Clinical Sciences, Department of Psychiatry,
University of Toronto

Dr. Krista L. Lanctôt has a PhD in Clinical Pharmacology from the University of Toronto, with additional training in pharmacoepidemiology.  In 2022, she was awarded the Bernick Chair in Geriatric Psychopharmacology. She is currently a Senior Scientist in Geriatric Psychiatry and in the Hurvitz Brain Sciences Program at Sunnybrook Research Institute, Research Co-Director in the Department of Psychiatry at Sunnybrook Health Sciences Centre and the Head of Neuropsychopharmacology Research. She is also a Full Professor of Psychiatry and Pharmacology/Toxicology, and Vice Chair of Basic and Clinical Sciences in the Department of Psychiatry at the University of Toronto, Toronto, Ontario, Canada. 

Dr. Lanctôt is an active researcher with over 375 published papers, and Editor of the 2021 book “Apathy: Clinical and Neuroscientific Perspectives from Neurology and Psychiatry”.  Her group’s research has focused on optimizing the pharmacotherapy of cognition and neuropsychiatric symptoms associated with dementia and in predementia states.  She currently holds grants as a PI from the Alzheimer’s Drug Discovery Foundation, Alzheimer’s Association US, Weston Brain Institute and Canadian Institutes of Health Research.  She is a full member of the School of Graduate Studies in the Faculty of Medicine, University of Toronto, previous winner of the Faculty of Medicine Graduate Education Award, and has trained more than 40 graduate students.


The activity is designed to help the learner describe: 

1.    the importance and prevalence of apathy in Alzheimer’s disease (AD).

2.    current diagnostic criteria for apathy in neurocognitive disorders.

3.    results of recent pharmacologic interventions for apathy in AD.


Decreased goal-directed behavior, or apathy, is commonly seen with in Alzheimer’s disease, yet not always recognized or treated. This talk will review recent advances have been made to address both these issues, and discuss next steps to move the field forward.  


CME/CE credit for Psychiatry Grand Rounds is only available during the live feed time and for a brief time immediately following. The code for this week's session is displayed at the opening and closing of the meeting and also in the Chair's Office Account Name during the meeting.


For CME/CE information about this session, please visit:



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Meeting ID: 289 458 185 37
Passcode: P3RiLP

This talk is sponsored by the Hollender Lecture Fund
Department of Psychiatry and Behavioral Sciences 
This educational activity received no commercial support.