Faculty Spotlight: Steven D. Townsend, Ph.D.

Steven D. Townsend is an Assistant Professor of Organic Chemistry at Vanderbilt University. Dr. Townsend is an expert in the chemical synthesis of biologically important molecules. A major topic of interest for his lab is the synthesis of homogeneous human milk oligosaccharides and related constructs to investigate their use as prebiotics in infant formula. He has numerous publications in premier international journals, including Proceedings of the National Academy of Science (USA), Angewandte Chemie International Edition and Journal of the American Chemical Society. Before being appointed to Vanderbilt in 2014, Townsend earned his PhD at Vanderbilt and then completed a postdoctoral research fellowship with Samuel J. Danishefsky at Memorial Sloan-Kettering Cancer Center and Columbia University... Click Dr. Townsend's photo to continue reading.

Postdoc Spotlight: Paulo Henrique de Melo, Ph.D.

Paulo Henrique de Melo, Ph.D. completed his undergraduate degree at Centro Universitário de Araraquara.  He did his Ph.D. at Universidade de São Paulo in Immunology. Paulo is a Postdoctoral Research Fellow in the lab of Carlos Henrique Serezani, Ph.D.... Click the image on the left to continue reading.

Faculty Spotlight: Ann Tate, Ph.D.

Dr. Ann Tate is an Assistant Professor in the Vanderbilt University Department of Biological Sciences. Her research focuses on understanding reciprocal ecological and evolutionary feedbacks between hosts and parasites, using a combination of theoretical and empirical approaches to zoom back and forth between the molecular details and the population level processes. Before moving to Vanderbilt Dr. Tate was a USDA NIFA postdoctoral fellow in the Department of Biology and Biochemistry at the University of Houston, mentored by Tim Cooper. She completed her Ph.D. in Ecology and Evolutionary Biology at Princeton University, and received her B.S. from Rice University.... Click Dr. Tate's photo to continue reading.

Recommended Reading - January 3rd, 2021

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense. Bosch M, et al. in Science, October 16, 2020 Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms. Beltra JC, et al.

Graduate Student Spotlight: Graces Morales

Grace is originally from Northern Virginia, but she earned her BS in Biotechnology and Molecular Bioscience from Rochester Institute of Technology in New York in 2018. Grace worked under Dr. Andre Hudson while in school. She then immediately joined Vanderbilt University in 2018 through the Interdisciplinary Graduate Program (IGP), and joined the Microbe-Host Interactions (MHI) Ph.D. graduate program. In the Schmitz and Hadjifrangiskou labs, Grace works on defining a molecular signature for uropathogenic E. coli. She utilizes bioinformatics and bacterial genetics techniques... Click the image on the left to continue reading.

How good is your memory? Debating the duration of COVID-19 immunity

In today’s COVID-19-centric world, it is easy to feel overwhelmed by headlines constantly broadcasting differing timelines of just how long this pandemic could last. One main determinant of the duration of lockdowns and social distancing is the development of a vaccine. The goal is “to create a vaccine that is safe and with good immunogenicity, meaning it stimulates a strong immune response.” Recent developments of COVID-19 vaccine design have promised ≥90% effectiveness, however, we are still missing the second half of the story. It is one achievement to instill COVID-19 immunity in the majority of vaccine recipients, but another to maintain this protection... Click the image to continue reading.

Cancer Vaccines: Are We There Yet?

The concept of immunity has intrigued humankind for centuries. From prehistoric times when disease was viewed as a form of punishment for wrong deeds by supernatural forces, to Louis Pasteur’s germ theory of disease, the field of immunology has come a long way. Our immune system comprises of a network of unique cells like macrophages, dendritic cells, T, B and natural killer cells housed by different organs that work to protect us from invading pathogens like bacteria, fungi and viruses. These cells have evolved to identify and neutralize foreign pathogens and keep us healthy. Thumbnail: IHME, Global Burden of Disease. OurWorldInData.org/cancer... Click the image to continue reading.

A COVID-19 Vaccine: Why We Need It and How We Get There Yesterday

Vaccines are typically developed through a lengthy, rigorous process that averages 10-15 years from inception to approval. The goal is to create a vaccine that is safe and with good immunogenicity, meaning it stimulates a strong immune response, to generate antibodies which can neutralize an invading pathogen. Given the high infectivity of COVID-19, the vast percentage of the population susceptible to the virus, and the burden it places on the healthcare system, the economy, and our lives, we need a vaccine much sooner than the normal 10-15-year timeline. To achieve a safe and effective vaccine within a reasonable time frame, a massive research effort within academia and the pharmaceutical industry must be undertaken in collaboration with and funded by the United States government... Click the image to continue reading.