Systematic discovery of antiphage defense systems in the microbial pangenome. Doron S, Sorek R, et al in Science, March 2, 2018 Pulmonary neuroendocrine cells amplify allergic asthma responses. Sui P,

Dr. Meena Madhur is an Assistant Professor of Medicine and Molecular Physiology and Biophysics. She is also an Associate Director of VI4. Her research focuses on how T cells and T cell-derived cytokines promote hypertension and renal/vascular dysfunction. Her lab was the first to demonstrate a critical role for the lymphocyte adaptor molecule LNK in hypertension and aortic disease. They also defined mechanisms by which the pro-inflammatory cytokine interleukin 17A (IL-17A) contributes to hypertension and renal sodium retention... Click Dr. Madhur's photo to continue reading.

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet. Olson C, Hsiao EY, et al in Cell, June 14, 2018 Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity. Kornberg MD, Snyder SH, et al in Science, April 27, 2018

Dr. Hadjifrangiskou is a microbiologist in the Departments of Urologic Surgery and Pathology, Microbiology, and Immunology; she is also part of our VI4 Leadership Committee as an Associate Director. Her lab studies the ways in which UPEC can sense changes in its surrounding environment and thereby accordingly alter its behavior as it transits through different host and environmental niches... Click Dr. Hadjifrangiskou's photo to continue reading.

Dr. Bordenstein is a biologist in the Departments of Biological Sciences and Pathology, Microbiology, and Immunology and we are fortunate to have him on our Leadership Committee as an Associate Director. He is also the founding director of the Vanderbilt Microbiome Initiative and worldwide science education program Discover the Microbes Within: The Wolbachia Project. His laboratory studies the functional, evolutionary and genetic principles that shape symbiotic interactions between animals, microbes, and viruses as well as the major consequences and applications of these symbioses to humans. Click Dr. Bordenstein's photo to continue reading.