ImmuKnow+ is a science publication designed and produced by the Vanderbilt Institute for Infection, Immunology and Inflammation (VI4). All articles are written by Vanderbilt affiliated students, faculty, and staff from various interdisciplinary departments. Our goal is to develop accessible, varied content to inform and educate the public on scientific discoveries and advances within VI4 and its collaborators through a multimedia platform. This publication aims to foster education in science, increase public engagement, and enhance communication between active researchers and the public.

Erin Calipari & Kristine Yoon - VI4 Scientists Doing Things

Dr. Erin Calipari and graduate student Kristine Yoon put their painting skills to the test while we asked them some questions about their the image on the left to watch!

Eric Skaar & Catherine Leasure - VI4 Scientists Doing Things

Dr. Eric Skaar and graduate student Catherine Leasure showcase their artistic talents with Perler bead kits while we asked them some questions about their the image on the left to watch!

The evolution of mRNA vaccines alongside SARS-COV-2

SARS-CoV-2 has mutated and evolved to partially evade the immune response generated from prior vaccination or infection. The development of mRNA technology allows for rapid reprogramming of the coding sequence to modify the immune response mounted by the vaccine. Although the long-term trajectory for vaccination recommendations remain unclear, the advanced mRNA vaccine technology allows for the combination and modulation of the targeted sequence to modify the potency of the immune response.... continue reading.

SARS-CoV-2 evolution and implications for immunity

While COVID-19 is no longer plaguing media outlets, the virus remains a serious threat to human health. Since the discovery of SARS-CoV-2, the virus and its transmissibility evolved. The Omicron variant is the dominant circulating virus that causes COVID-19 in the United States and is capable of evading pre-existing immunity, causing serious public health concern. In fact, the greatest number of COVID-19 related hospitalizations occurred during the first Omicron wave. With high burdens of respiratory syncytial virus (RSV) and influenza this season, it is important to remain vigilant and take steps to prevent severe COVID-19 illness.....continue reading.