The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - November 19th, 2023
- Type I interferons and Mycobacterium tuberculosis whole cell lysate induce distinct transcriptional responses in M. tuberculosis infection. Mutua F, et al. in Tuberculosis, September 11, 2023
- Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection. Li Y, et al. in Journal of Virology, August 28, 2023
- Divergent Actions of Renal Tubular and Endothelial Type 1 IL-1 Receptor Signaling in Toxin-Induced AKI. Ren J, et al. in Journal of the American Society of Nephrology, October 1, 2023
- CD8 T cell tolerance results from eviction of immature autoreactive cells from the thymus. Badr M, et al. in Science, November 2, 2023
- Sialic acid plays a pivotal role in licensing Citrobacter rodentium’s transition from the intestinal lumen to a mucosal adherent niche. Liang Q, et al. in PNAS, July 3, 2023
Recommended Reading - October 8th, 2023
- ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy. Seo DO, et al. in Science, January 13, 2023
- Heteroresistance to cefepime– taniborbactam in metallo-β-lactamaseencoding Enterobacterales. Weiss D, et al. in The Lancet, July 5, 2023
- Effect of Micro-Patterned Mucin on Quinolone and Rhamnolipid Profiles of Mucoid Pseudomonas aeruginosa under Antibiotic Stress. Bohn, P W, et al. in ACS Infectious Diseases, December 13, 2022
- Systemic application of bone-targeting peptidoglycan hydrolases as a novel treatment approach for staphylococcal bone infection. Keller A, et al. in mBio, September 28, 2023
- Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome. Baghdassarian H, et al. in The New England Journal of Medicine, June 15, 2023
Recommended Reading - September 17th, 2023
- Phage diversity in cell-free DNA identifies bacterial pathogens in human sepsis cases. Haddock N, et al. in Nature Microbiology, June 12, 2023
- Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae. Vidakovic L, et al. in Cell, May 8, 2023
- PD-1 maintains CD8 T cell tolerance towards cutaneous neoantigens. Damo M, et al. in Nature, June 21, 2023
- Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential. Wang J, et al. in Nature Communications, July 10, 2023
- Influenza A virus coinfection dynamics are shaped by distinct virus-virus interactions within and between cells. Delima G, et al. in PLOS Pathogens, March 2, 2023
Recommended Reading - August 8th, 2023
- The enteric nervous system relays psychological stress to intestinal inflammation. Schneider K, et al. in Cell, May 5, 2023
- Viriforms—A New Category of Classifiable Virus-Derived Genetic Elements. Kuhn J & Koonin E. in Biomolecules, February 13, 2023
- De novo evolution of macroscopic multicellularity. Bozdag G. O, et al. in Nature, May 10, 2023
- Droplet Tn-Seq identifies the primary secretion mechanism for yersiniabactin in Yersinia pestis. Price, S, et al. in EMBO Reports, July 28, 2023
- Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse. Stinchcombe J, et al. in Science, May 23, 2023
Recommended Reading - July 9th, 2023
- Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Buckley, P et al. in Cell Host & Mircobe, May 10, 2023
- Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation. Li Y, et al. in Nature Communications, May 5, 2023
- Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology . Gullotta G, et al. in Nature Immunology, May 15, 2023
- Infection leaves a genetic and functional mark on the gut population of a commensal bacterium. Tawk C, et al. in Cell Host & Microbe, May 10, 2023
- Mirusviruses link herpesviruses to giant viruses. Gaia M, et al. in Nature, April 19, 2023
Recommended Reading - June 4th, 2023
- Role of Caspases and Gasdermin A during HSV-1 Infection in Mice. Li L, et al. in Viruses, September 13, 2022
- S+C121:C124tunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes. Culemann S, et al. in Journal of Experimental Medicine, March 28, 2023
- Profiling the human intestinal environment under physiological conditions. Shalon D, Et al. in Nature, May 10, 2023
- Exogenously Scavenged and Endogenously Synthesized Heme Are Differentially Utilized by Mycobacterium tuberculosis. Donegan R, et al. in Microbiology Spectrum, September 28, 2022
- Spatial transcriptome uncovers rich coordination of metabolism in E. coli K12 biofilm. Wang T, et al. in Nature Chemical Biology, April 13, 2023
Recommended Reading - May 8th, 2023
- Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis. Weindel C, et al. in Cell, August 18, 2022
- CTCF mediates CD8+ effector differentiation through dynamic redistribution and genomic reorganization. Liu J, et al. in Journal of Experimental Medicine, April 23, 2023
- Exploring Masses and Internal Mass Distributions of Single Carboxysomes in Free Solution Using Fluorescence and Interferometric Scattering in an Anti-Brownian Trap. Lavania A, et al. in The Journal of Physical Chemistry B, October 25, 2022
- STAT3 regulates CD8+ T cell differentiation and functions in cancer and acute infection. Sun Q, et al. in Journal of Experimental Medicine, April 3, 2023
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins. Oh C, et al. in Cell Reports, November 22, 2022
Recommended Reading - April 16th, 2023
- Coordination of bacterial cell wall and outer membrane biosynthesis. Hummels K, et al. in Nature, March 1, 2023
- Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment. Onkar S, et al. in Nature Cancer, March 16, 2023
- SARS-CoV-2 Omicron (B.1.1.529) shows minimal neurotropism in a double-humanized mouse model. Alves, RPdS et al. in Antiviral Research, April 1, 2023
- Glycogen Metabolism in Candida albicans Impacts Fitness and Virulence during Vulvovaginal and Invasive Candidiasis. Miao, J et al. in mBio, February 22, 2023
- GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection. Amaral E, et al. in Journal of Experimental Medicine, September 7, 2022
Recommended Reading - March 5th, 2023
- CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor. Prokhnevska N, et al. in Immunity, December 21, 2022
- Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states. Ma P, et al. in Cell, February 16, 2023
- Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks. Amato K, et al. in Nature Communications, June 14, 2022
- The maternal prenatal and offspring early-life gut microbiome of childhood asthma phenotypes. Lee-Sarwar K, et al. in Allergy, September 15, 2022
- A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli. Birkholz E, et al. in Cell Reports, August 16, 2022
Recommended Reading - February 5th, 2023
- Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation. Hata M, et al. in Science, January 6, 2023
- Functional T cells are capable of supernumerary cell division and longevity. Soerens A, et al. in Nature, December 5, 2022
- Chlamydia repurposes the actin-binding protein EPS8 to disassemble epithelial tight junctions and promote infection. Dolat L, et al. in Cell Host & Microbe, December 14, 2022
- Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses. Cuesta S, et al. in Cell Host & Microbe, November 9, 2022
- Fetal and maternal NLRP3 signaling is required for preterm labor and birth. Motomura K, et al. in The Journal of Clinical Investigation Insights, August 22, 2022
