Glaucoma Clinical Trials Study

COAST Study (Clarifying the Optimal Application of SLT Therapy)

Principal Investigator, Rachel Kuchtey, MD, PhD, and Study Coordinator, Marybeth Carter are collaborating with researchers in the US and UK who have joined with the National Eye Institute to investigate the optimal energy level and frequency of laser therapy to treat glaucoma. Selective laser trabeculoplasty (SLT) has been a treatment option for newly diagnosed open-angle glaucoma or ocular hypertension for nearly 20 years. However, few studies have specifically compared multiple energy levels directly in a head-to-head fashion. We believe that low energy SLT may help people avoid the need to use eye drop medications for a longer time than standard energy SLT. 

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Jeffrey Kammer, MD, and Crystal Nicholson are starting a clinical trial study with iStar medical to understand whether the study device, the MINI SO627, can be safely implanted in the patient’s eye to decrease the pressure inside of the eye. The implant MINI SO627 is made of 100% medical grade silicone, and it is 5.0 mm long, 1.1 mm wide, and 0.6 mm thick. The implant is made of a porous material which aims to increase the movement of fluid out of the front of the eye to the surrounding tissue. This higher fluid flow can reduce the eye pressure. We plan to recruit 10 patients diagnosed with primary open-angle glaucoma.



Jeffrey Kammer, MD, and Crystal Nicholson are participating in a clinical trial to test the safety and effectiveness of the Bimatoprost Implant System versus a topical ocular drop for glaucoma, Timolol Maleate (Timolol), in participants requiring cataract surgery and diagnosed with ocular hypertension (OHT) or open -angle glaucoma (OAG). The system consists of two (2) silicone drug pads containing the drug Bimatoprost. The Bimatoprost Implant System is assembled with an Intraocular Lens (IOL) and implanted during cataract surgery. The drug Bimatoprost is continuously released into your study eye and can last up to 3 years. You will receive a $100, $125, $150, $175, or $200 gift card depending on the visit for each visit. Please email Crystal Nicholson or call 615-936-0971 if you are interested.