W. Stuart Reynolds MD, MPH

Associate Professor
Department of Urology
Fellowship Director
Female Pelvic Medicine and Reconstructive Surgery Fellowship
Division of Reconstructive Urology and Pelvic Health

Medical School: Pennsylvania State University, Milton S. Hershey College of Medicine
Residency: University of Chicago Medical Center
Fellowship: Vanderbilt Female Pelvic Medicine and Reconstructive Surgery Fellowship
Clinical Interests: Pelvic Prolapse, Urinary Incontinence, Female Pelvic Medicine, Genitourinary Reconstructive Surgery, Neurogenic Bladder

Dr. Reynolds divides his time between clinical and translational research on functional bladder disorders, education of urology residents and FPMRS fellows, and care of patients with pelvic floor and urinary disorders. He is active in the Society of Urodynamics, Female Pelvic Medicine, and Urogenital Reconstruction (SUFU) and was awarded the SUFU Paul Zimskind award for excellence and leadership in the field within 10 years of completion of training in 2019.

Research Information

Dr. Reynolds is currently funded by scientific grants from NIDDK and SUFU Research Foundation. His primary research interests are

  • Clinical Epidemiology and Health Services Research as applied to benign conditions of genitourinary system
  • Clinical outcomes and translational research in benign urologic and pelvic floor disorders
  • Comparative Effectiveness in benign urologic and pelvic floor diseases

Current research projects include

Pain mechanisms in overactive bladder and functional bladder disorders.

This project examines how sensory and pain pathways, specifically central sensitization, impact on Overactive Bladder symptoms and treatment outcomes. The goal of this research is to identify a biomarker for sensory nerve dysfunction that can help distinguish individuals with OAB based on underlying pathophysiologic mechanisms. 

Hypothetical roles of central sensitization in overactive bladder

Selected Publications

How restroom availability and toilet environments impact bladder health and benign urologic conditions.

This area of research investigates the relationships between toilet behaviors and habits, restroom environment restrictions and limitations, and bladder symptoms. The goal of this research is to better understand how external influences, such as access to restrooms, impact on individuals’ toileting experiences and bladder health.


Figure 2 - proportion of women who avoid public restrooms and whyNavigating restrooms: A biopsychosial framework for women

Selected Publications

Microbiologic interactions with host genitourinary system

This research focuses on urinary microbes, including E. Coli, and how they access and damage the urinary system, causing infection and symptoms. This is a collaborative effort with researchers in Vanderbilt Institute for Infection, Immunology, and Inflammation.

Click here to read more.

Psychosocial impacts on interstitial cystitis and bladder pain syndrome.

This work examines how psychosocial factors in chronic pain influence ICBPS and how initiation of self-administered cognitive behavioral therapy can improve symptoms and functioning in patients. 

Selected Publications

Spinal cord functional MRI signaling in functional bladder disorders.

This project explores the novel application of spinal cord functional MRI techniques to identifying disease pathways in neurogenic and non-neurogenic OAB. This project is a collaborative endeavor with researchers in the Vanderbilt University Institute for Imaging Science.