Introduction

With so many innovative research technologies available in the Vanderbilt Community, it is likely that researchers from a broad spectrum of disciplines could find themselves in a scenario where they may be planning to work with biological materials that are potentially infectious to humans.  It’s important for those planning this work to consider all factors that could lead to (or increase the likelihood of) an accidental exposure to infectious material before they commit to receiving these materials and starting this work. Both risk assessment and institutional biosafety approval of biosafety/biocontainment procedures is necessary to ensure that this work will be done safely and in compliance with applicable standards.  

Please Note:  You should not receive or accept COVID-19 samples or related materials before a risk assessment is completed and approved by your entity’s Institutional Biosafety Committee (IBC).

Planning for work with COVID-19/SARS-CoV-2 associated materials?

In response to the COVID-19 pandemic that is impacting public health worldwide, the "call" has gone out to the scientific research community to develop screening tests and therapeutics, as well as studies to better understand the virus itself.

If you are planning to work with COVID-19 clinical specimens or SARS-CoV-2 associated materials, it is important to have a risk assessment completed in conjunction with VEHS Biosafety before finalizing these plans or submitting a grant proposal. You can initiate this process by completing and submitting a VEHS Biosafety Intake Form for Research with COVID-19/SARS-CoV-2 materials.

Additionally, please review the COVID-19/SARS-CoV-2 material biosafety action grid to determine actions that will likely apply to your research plans. If your materials or activities are not specifically addressed in this grid, but are related to research involving COVID-19/SARS-CoV-2 materials, please contact Robin Trundy or Bettye Ridley for assistance.

Biosafety Recommendations - National Organization Links:

Vanderbilt COVID-19 Research Biosafety Links:

Institutional Biosafety Committee (IBC) Approval Considerations

Any Vanderbilt researcher who is planning to receive any biological specimens from COVID-19 patients (or any other materials associated with the SARS-CoV-2 virus) must submit a biological materials registration or amendment to their entity’s IBC.  If you submit a VEHS Biosafety Intake Form for Research with COVID-19/SARS-CoV-2 materials, VEHS Biosafety will send you an IBC registration or amendment form (as applicable) with instructions regarding completion. 

The IBC must review and approve the risk assessment and biocontainment plan for the proposed activities before shipment/transfer of these materials is initiated. (Note: This is not a new requirement but a reminder of the existing requirements for using any potentially infectious materials that have not been previously documented with and approved by the IBC.)

Other policies related to the receipt and work with materials potentially containing infectious agents include:

Please note that Biological Material Registration forms are not available online at this time. Please contact Robin Trundy or request assistance via the VEHS Biosafety email account to file a biological materials registration or amendment.

Additional risk assessment and biocontainment resources: