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Diagnostic Criteria

POTS is defined as a sustained heart rate increment of >30 beats/minute within 10 min of standing or head-up tilt in the absence of orthostatic hypotension (the blood pressure does not drop by more than 20/10 mmHg).


For patients 12-19 years old, the heart rate must increase by at least 40 beats/minute.


This may be accompanied by symptoms of cerebral hypoperfusion and autonomic overactivity that are relieved by lying down.