Daniel B. Brown, M.D., FSIR
Daniel B. Brown, MD, FSIR, is Professor of Radiology & Radiological Sciences as well as Biomedical Engineering at Vanderbilt University Medical Center. He currently serves as the Interim Chair in Radiology, as well as Vice-Chair of Innovation and Clinical Research.
Dr. Brown has over 260 published articles and scientific abstracts and has given more than 300 invited talks. He has served on the Executive Council of the Society of Interventional Radiology and Society of Interventional Oncology. His research has focused primarily on locoregional therapy of cancer, including Cryoablation as well as other thermal ablation modalities.
Section: Interventional Oncology
Publications
Agarwal R, Matsuoka LK, Brown DB. Liver-Directed and Systemic Therapy Options for Hepatocellular Carcinoma. J Natl Compr Canc Netw 2022;20:1-5, in press.
Emmons EC, Bishay S, Du Liping, Krebs H, Gandhi RT, Collins ZS, O’Hara R, Akhter N, Wang EA, Grilli C, Brower JS, Peck SR, Petroziello M, Abdel Aal AK, Golzarian J, Kennedy AS, Matsuoka L, Sze DY, Brown DB. Survival and Toxicities after 90Y Transarterial radioembolization of metastatic colorectal cancer in the RESiN Registry. Radiology, in press
Lebeck Lee CM, Ziogas IA, Agarwal R, Alexopoulos SP, Ciombor KK, Matsuoka LK, Brown DB, Eng C. A Contemporary Systematic Review on Liver Transplantation for Unresectable Liver Metastases of Colorectal Cancer. Cancer 2022; 128:2243-2257. doi: 10.1002/cncr.34170
Wong TY, Zhang K, Gandhi RT, Collins ZS, O’Hara R, Wang EA, Vaheesan K, Matsuoka L, Sze DY, Kennedy AS, Brown DB. Long-Term Outcomes following 90Y Radioembolization of Neuroendocrine Liver Metastases: Evaluation of the Radiation-Emitting SIR-Spheres in Non-Resectable liver tumor (RESiN) Registry. BMC Cancer 2022;22:224 https://doi.org/10.1186/s12885-022-09302-z
Servin F, Collins JA, Heiselman JS, Frederick-Dyer KC, Planz VB, Geevarghese SK, Brown DB, Miga MI. Fat Quantification Imaging and Biophysical Modeling for Patient-Specific Forecasting of Microwave Ablation Therapy. Front Physiol 2022 Feb 3;12:820251 PMID: 38185606 doi: 10.3389/fphys.2021.820251. eCollection 2021.
Tierney J, Luchies A, Khan C, Baker J, Brown D, Byram B, Berger M. Training Deep Network Ultrasound Beamformers with Unlabeled In Vivo Data. IEEE Transactions on Medical Imaging. 2022;41:158-171. doi: 10.1109/TMI.2021.3107198
Benson AB, D’Angelica MI, Abbott DE, Anaya DA, Anders R, Are C, Bachini M, Borad M, Brown D, Burgoyne A, Chahal P, Chang DT, Cloyd J, Covey AM, Glazer ES, Goyal L, Hawkins WG, Iyer R, Jacob R, Kelley RK, Kim R, Levine M, Palta M, Park JO, Raman S, Reddy S, Sahai V, Schefter T, Singh G, Stein S, Vauthey JN, Venook AP, Yopp A, McMillian NR, Hochstetler C, Darlow SD. Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2021;19:541-565.
Frantz S, Matsuoka L, Vaheesan K, Petroziello M, Golzarian J, Wang E, Gandhi R, Collins Z, Brower J, Rachakonda VM, Du L, Kennedy AS, Sze DY, Lee J, Brown DB. Multi-Center Evaluation of Survival and Toxicities following Radioembolization: analysis of the RESiN Registry. J Vasc Interv Radiol 2021;32:845-852.
Ozgun K, Stanton JT, Baker J, Borgmann A, Brown D, Byram B. Non-contrast power Doppler imaging with multidimensional clutter filtering for assessment of transarterial chemoembolization for hepatic malignancy. SPIE, Medical Imaging: Ultrasonic Imaging and Tomography. https://doi.org/10.1117/12.2582109
Brown D, Krebs H, Brower J, O’Hara R, Wang E, Vaheesan K, Du L, Matsuoka L, D’Souza D, Sze D, Golzarian J, Gandhi R, Kennedy A. Incidence and Risk Factors for Sustained Hepatic Function Toxicity 6 Months after Y90 Radioembolization: Analysis of the Radiation-Emitting SIR-spheres In Non-resectable liver tumor (RESIN) registry. J Gastrointest Oncol 2021;12:639-657 http://dx.doi.org/10.21037/jgo-20-346
Lakhoo J, Adams R, Dave A, Luo L, Vargo CJ, Isaacson AJ, Sher A, Fischman A, Yee DC, Ryan S, Shreejal P, Duchac D, Brown DB. Radiopaque beads loaded with doxorubicin in the treatment of patients with hepatocellular carcinoma: a retrospective multi-center study. Cancer Treat Res Commun 2020;25:100208, https://doi.org/10.1016/j.ctarc.2020.100208.
Buettner S, Braat AJAT, Margonis GA, Brown DB, Taylor KB, Borgmann AJ, Kappadath SC, Mahvash A, Ijzermans JNM, Weiss MJ, Lamaraca A, Bell JK, Valle JW, Hagendoorn J, Koerkamp BG, Sze DY, Lam MGEH. Yttrium-90 radioembolization in intrahepatic cholangiocarcinoma: a multicenter retrospective analysis. J Vasc Interv Radiol 2020;31:1035-1043. DOI: 10.1016/j.jvir.2020.02.008
Tierney J, Baker J, Brown D, Wilkes D, Byram B. Independent Component-Based Spatiotemporal Clutter Filtering for Slow Flow Ultrasound. IEEE Transactions on Medical Imaging. 2020; 39(5):1472-1482. Doi: 10.1109/TMI.2019.2951465
Tierney J, Baker J, Borgmann A, Brown D, Byram B. Non-contrast power Doppler ultrasound imaging for early assessment of trans-arterial chemoembolization of liver tumors. Sci Rep 2019;10:9(1):13020 doi: 10.1038/s41598-019-49448-8.
Cruz JC, Watchmaker JM, Albin MM, Wang L, Wu G, Baker JC, Fritsche MR, Alexopoulos SP, Matsuoka L, Fleming JW, Su J, Borgmann AJ, Banovac F, Brown DB. Neutrophil/Lymphocyte Ratio Predicts Increased Risk of Immediate Progressive Disease following Chemoembolization of Hepatocellular Carcinoma. J Vasc Interv Radiol [print-electronic]. 2019 Oct 10/24/2019; PMID: 31669086, PII: S1051-0443(19)30686-4, DOI: 10.1016/j.jvir.2019.08.001, ISSN: 1535-7732.
Hevert EAC, Howser CG, Gould ML, Brown DB. Ablative, Endovascular, and Biliary Interventions for Patients with Pancreatic Cancer. Semin Intervent Radiol [print-electronic]. 2019 Aug; 36(3): 203-12. PMID: 31435128, PMCID: PMC6699965, PII: 001149, DOI: 10.1055/s-0039-1693118, ISSN: 0739-9529.
Klimkowski S, Baker JC, Brown DB. Red Flags, Pitfalls, and Cautions in Y90 Radiotherapy. Tech Vasc Interv Radiol [print-electronic]. 2019 Jun; 22(2): 63-9. PMID: 31079712, PII: S1089-2516(19)30012-5, DOI: 10.1053/j.tvir.2019.02.005, ISSN: 1557-9808.
Perez AW, Watchmaker JM, Brown DB, Banovac F. Association between Periprocedural Neutropenia and Early Infection-related Chest Port Removal. Radiology [print-electronic]. 2019 May; 291(2): 513-8. PMID: 30747596, DOI: 10.1148/radiol.2019182175, ISSN: 1527-1315.
Watchmaker JM, Lipnik AJ, Fritsche MR, Baker JC, Mouli SK, Geevarghese S, Banovac F, Omary RA, Brown DB. Are prophylactic antibiotics necessary prior to transarterial chemoembolization for hepatocellular carcinoma in patients with native biliary anatomy?. J Surg Oncol [print-electronic]. 2018 May; 117(6): 1312-7. PMID: 29513895, DOI: 10.1002/jso.24993, ISSN: 1096-9098.
Fritsche MR, Watchmaker JM, Lipnik AJ, Baker JC, Geevarghese S, Banovac F, Omary RA, Brown DB. Outpatient Transarterial Chemoembolization of Hepatocellular Carcinoma: Review of a Same-Day Discharge Strategy. J Vasc Interv Radiol [print-electronic]. 2018 Feb 2/23/2018; PMID: 29478795, PII: S1051-0443(17)31038-2, DOI: 10.1016/j.jvir.2017.11.018, ISSN: 1535-7732.
Mouli S, Baker JC, Brown DB. Interventional Oncology Service Development. Semin Intervent Radiol [print-electronic]. 2017 Jun; 34(2): 182-6. PMID: 28579686, PMCID: PMC5453768, PII: 00999, DOI: 10.1055/s-0037-1601853, ISSN: 0739-9529.
Taussig MD, Irene Koran ME, Mouli SK, Ahmad A, Geevarghese S, Baker JC, Lipnik AJ, Banovac F, Brown DB. Neutrophil to lymphocyte ratio predicts disease progression following intra-arterial therapy of hepatocellular carcinoma. HPB (Oxford) [print-electronic]. 2017 Feb 2/9/2017; PMID: 28190710, PII: S1365-182X(17)30043-6, DOI: 10.1016/j.hpb.2017.01.013, ISSN: 1477-2574.
Koran ME, Stewart S, Baker JC, Lipnik AJ, Banovac F, Omary RA, Brown DB. Five percent dextrose maximizes dose delivery of Yttrium-90 resin microspheres and reduces rates of premature stasis compared to sterile water. Biomed Rep [print-electronic]. 2016 Dec; 5(6): 745-8. PMID: 28105342, PMCID: PMC5228356, PII: BR-0-0-799, DOI: 10.3892/br.2016.799, ISSN: 2049-9434.
Koran ME, Lipnik AJ, Baker JC, Banovac F, Omary RA, Brown DB. Procedural Impact of a Dedicated Interventional Oncology Service Line in a National Cancer Institute Comprehensive Cancer Center. J Am Coll Radiol [print-electronic]. 2016 Jun 6/11/2016; PMID: 27297700, PII: S1546-1440(16)30307-6, DOI: 10.1016/j.jacr.2016.04.033, ISSN: 1558-349X.
Gaba RC, Lewandowski RJ, Hickey R, Baerlocher MO, Cohen EI, Dariushnia SR, Janne d'Othée B, Padia SA, Salem R, Wang DS, Nikolic B, Brown DB, . Transcatheter Therapy for Hepatic Malignancy: Standardization of Terminology and Reporting Criteria. J Vasc Interv Radiol [print-electronic]. 2016 Apr; 27(4): 457-73. PMID: 26851158, PII: S1051-0443(15)02007-2, DOI: 10.1016/j.jvir.2015.12.752, ISSN: 1535-7732.