About the Delpire Lab

Director, Anesthesiology Basic Science Division

B.H. Robbins Director in Anesthesiology Research

Rainelli is currently investigating regulatory mechanisms of SPAK/OSR1 kinases.

Rainelli attended Meharry Medical college where he obtained his Ph.D in biomedical sciences. He also attended the University of Montreal in Quebec where he majored in biochemistry (B.S.), and Laval University where he obtained a Masters in Sciences in Molecular Biology. 

Mohammed is currently investigating the role of KCC3a in K⁺ loss in alkalemia

Mohammed Ferdaus obtained his Ph.D. at Shimane University, Izumo, Japan. He then did a Post-Doctoral Fellowship in the Division of Nephrology & Hypertension at Oregon Health and Science University in Portland, Oregon followed by a Post-Doctoral Fellowship in the Department of Pharmacology & Experimental Therapeutics at Boston University, Massachusetts, prior to joining the laboratory.

Training in Fundamental Neuroscience              2015-2017

Vanderbilt Program in Molecular Medicine         2015-2018

Bianca is involved with studies of KCC3; understanding how genetically-modified mutant mice can be used to understand the molecular mechanisms leading to peripheral nerve disease in humans. 

Bianca attended the University of Rochester where she obtained her B.S. in neuroscience.

Training in Fundamental Neuroscience 2016-2018

Salma received a B.S. in Chemistry from Virginia Commonwealth University.

(2009 - 2014)  Studied the relationship between KCC2 and pain perception

                       Studied the binding of peptides and inhibitors to the SPAK kinase binding pocket

(2003 - 2011) Studied the regulation of NKCC1 by WNK4 and SPAK/OSR1 kinases

​Published 16 manuscripts in the lab!

(2012 - 2014) Identified a protease that cleaves SPAK

J. Biol. Chem. 289: 29273-29284 (2014)

(2000 - 2003) Discovered and studied SPAK / cation-chloride cotransporters interaction

J. Biol. Chem. 277: 50812-50819, 2002.

J. Biol. Chem. 278: 52848‑52856, 2003.

(2010 - 2014) Studied the regulation of NKCC1 by Cab39, WNK4, and SPAK

​Am. J. Physiol. Cell Physiol. 303(11), C1198-C1205, 2012. 

J. Biol. Chem. 289: 17680-17688, 2014. 

Assistant Professor, Department of Pharmacology, Vanderbilt

Graduated in 2007

NIH-NRSA (2004-2006)

Forma Fisher-Scientific

Graduated in 2014

NIH, Office of Director

Graduated in 2008

Regulation of the neuronal K⁺-Cl^- cotransporter, KCC2, by protein associated with myc

AHA-Fellowship (2004-2006), AAAS Mass Media Science and Engineering Fellowship Summer 2004

To read a bit about Nicole's current position at NIH and some advice she offers to graduate students click here

PostDoctoral Fellow, Pediatrics - Human Gene Therapy, Stanford University

Research Scientist, Gladstone Institute

Graduated in 2007

KCC2 and NKCC1 in the control of neuronal Cl^- and brain excitability

Interdisciplinary Graduate Program 2015-2016

Training in Fundamental Neuroscience 2016- 2019

M.S. (Neuroscience), Vanderbilt University 2019

Cara received her B.S. in Liberal Arts and Sciences from the University of Illinois Urbana-Champaign in 2015.

Senior, University of Tennessee - Knoxville

Jordan worked on understanding cell physiology with OXR1 receptor and NKCC1. 

Jordan is currently working towards his goals of becoming a physician-scientist with a focus in oncology.