About the Delpire Lab

Principal Investigator

  • Eric Delpire, Ph.D.

    Professor of Anesthesiology and Molecular and Biophysics (MPB)
    Light Hall 1265
    Lab Phone
    615-343-7409
    Lab Address
    Light hall
    2215B Garland Ave
    Nashville
    Tennessee
    37232

    Director, Anesthesiology Basic Science Division

    B.H. Robbins Director in Anesthesiology Research

Post-docs

  • Rainelli Koumangoye

    Research Instructor
    Light Hall 1255

    Rainelli is currently investigating regulatory mechanisms of SPAK/OSR1 kinases.

     

    Rainelli attended Meharry Medical college where he obtained his Ph.D in biomedical sciences. He also attended the University of Montreal in Quebec where he majored in biochemistry (B.S.), and Laval University where he obtained a Masters in Sciences in Molecular Biology. 

Graduate students

  • Bianca Flores

    Graduate student
    Neuroscience

    Training in Fundamental Neuroscience              2015-2017

    Vanderbilt Program in Molecular Medicine         2015-2018

     

    Bianca is involved with studies of KCC3; understanding how genetically-modified mutant mice can be used to understand the molecular mechanisms leading to peripheral nerve disease in humans. 

    Bianca attended the University of Rochester where she obtained her B.S. in neuroscience.

  • Salma Omer

    Graduate student
    Neuroscience Program

    Training in Fundamental Neuroscience 2016-2018

    Salma received a B.S. in Chemistry from Virginia Commonwealth University.

Former Fellows

  • Thomas Austin, M.D.

    Associate Professor of Anesthesiology
    Emory University

    (2009 - 2014)  Studied the relationship between KCC2 and pain perception

                           Studied the binding of peptides and inhibitors to the SPAK kinase binding pocket

     

  • Kenneth Gagnon, Ph.D

    Assistant Professor
    Department of Medicine, University of Louisville

    (2003 - 2011) Studied the regulation of NKCC1 by WNK4 and SPAK/OSR1 kinases

    ​Published 16 manuscripts in the lab!

  • (2012 - 2014) Identified a protease that cleaves SPAK

    J. Biol. Chem. 289: 29273-29284 (2014)

  • (2000 - 2003) Discovered and studied SPAK / cation-chloride cotransporters interaction

    J. Biol. Chem. 277: 50812-50819, 2002.

    J. Biol. Chem. 278: 52848‑52856, 2003.

  • (2010 - 2014) Studied the regulation of NKCC1 by Cab39, WNK4, and SPAK

    Am. J. Physiol. Cell Physiol. 303(11), C1198-C1205, 2012. 

    J. Biol. Chem. 289: 17680-17688, 2014. 

Former Graduate Students

  • Assistant Professor, Department of Pharmacology, Vanderbilt

    Graduated in 2007

    NIH-NRSA (2004-2006)

  • NIH, Office of Director

    Graduated in 2008

    Regulation of the neuronal K+-Cl- cotransporter, KCC2, by protein associated with myc

    AHA-Fellowship (2004-2006), AAAS Mass Media Science and Engineering Fellowship Summer 2004

    To read a bit about Nicole's current position at NIH and some advice she offers to graduate students click here

     

  • PostDoctoral Fellow, Pediatrics - Human Gene Therapy, Stanford University

  • Research Scientist, Gladstone Institute

    Graduated in 2007

    KCC2 and NKCC1 in the control of neuronal Cl- and brain excitability

  • Cara C. Schornak

    Graduate Student, Neuroscience Program

    Interdisciplinary Graduate Program 2015-2016

    Training in Fundamental Neuroscience 2016- 2019

    M.S. (Neuroscience), Vanderbilt University 2019

    Cara received her B.S. in Liberal Arts and Sciences from the University of Illinois Urbana-Champaign in 2015.

Former Undergraduate Students

  • Senior, University of Tennessee - Knoxville

    Jordan worked on understanding cell physiology with OXR1 receptor and NKCC1. 

    Jordan is currently working towards his goals of becoming a physician-scientist with a focus in oncology.