Kamal Jouad, PhD
Development of radiopharmaceuticals and opticals agent for preclinical and clinical research.
My research project aims to fully automated manufacturing of imaging probes for precision surgery utilizing cancer-targeted moieties (antibodies, affibodies, small molecules, etc.) conjugated to radioisotopes (89Zr, 111In, 18F, 68Ga, etc.) or optical fluorescent dye (IRDye800, ICG)
Research Information
Patent
1- Sandrine Lamande-Langle, Nadia Pellegrini-Moïse, Kamal Jouad, Yann Bernhard, Katalin Selmeczi.
Cyanine dimers for photothermal treatment of cancer guided by fluorescence/photoacoustic imaging.
WO2025210124.
Journal Articles
Kamal Jouad, Svetlana V. Eliseeva, Guillaume Collet, David Da Silva, Marie-Aude Hiebel, Nabil El Brahmi, Mohamed Akssira, Stéphane Petoud, Saïd El Kazzouli, and Franck Suzenet. Near-Infrared Emitting Poly(amidoamine) Dendrimers with an Anthraquinone Core toward Versatile Non-Invasive Biological Imaging. Biomacromolecules 2022, 23 (3), 1392-1402
Julen Ariztia, Kamal Jouad, Valérie Jouan-Hureaux, Julien Pierson, Charlotte Collet, Bertrand Kuhnast, Katalin Selmeczi, Cédric Boura, Sandrine Lamandé-Langle, and Nadia Pellegrini Moïse. Clickable C-Glycosyl Scaffold for the Development of a Dual Fluorescent and [18F]fluorinated Cyanine-Containing Probe and Preliminary In Vitro/Vivo Evaluation by Fluorescence Imaging. Pharmaceuticals 2022, 15 (12), 1490
JKamal Jouad, Emilien Mengel, Katalin Selmeczi, Mathilde Bouché, Charlotte Collet-Defossez, Nadia Pellegrini Moïse, Sandrine Lamandé-Langle. Multimodal PET/PAI/FLI imaging probe based on meso-O-alkyl heptamethine cyanine: Synthesis, 18F-radiolabelling and photophysical characterizations. Dyes and Pigments 2024, 223, 111995
Timothé Vucko, Julen Ariztia, Kamal Jouad, Dylana Chapeau, Benjamin Mourot, Valérie Jouan-Hureaux, Charlotte Collet, Cédric Boura, Katalin Selmeczi, Nadia Pellegrini-Moïse, Sandrine Lamande-Langle. Cyanine-based [18F]F-C-glycosyl dual imaging probe: synthesis, physico-chemical characterization, in vitro binding evaluation and direct [18F]fluorination. New Journal of Chemistry 2023, 47 (6), 3055 - 30662
Ashtyn McAdoo, Kamal Jouad, Eben Rosenthal, Adam Rosenberg. Rapid Assessment of Target-Binding Fractions in Theranostic and Imaging Agents Using Size-Exclusion HPLC. EJNMMI Radiopharmacy and Chemistry. EJNMMI radiopharm. chem. 2026.
Kamal Jouad, Marisa Hom, Eben Rosenthal, Adam Rosenberg. Automated cGMP optical labeling of FDA approved antibodies for human use. Nature Protocols 2025, 21, 3795–3813.
Kamal Jouad, Emilien Mengel, Katalin Selmeczi, Mathilde Bouché, Charlotte Collet-Defossez, Nadia Pellegrini-Moïse, Sandrine Lamandé-Langle. Multimodal PET/PAI/FLI imaging probe based on meso-O-alkyl heptamethine cyanine: Synthesis, 18F-radiolabelling and photophysical characterizations. Dyes and Pigments 2024, 223, 111995.
Kamal Jouad, Svetlana V. Eliseeva, Guillaume Collet, David Da Silva, Marie-Aude Hiebel, Nabil El Brahmi, Mohamed Akssira, Stéphane Petoud, Saïd El Kazzouli, and Franck Suzenet. Near-Infrared Emitting Poly(amidoamine) Dendrimers with an Anthraquinone Core toward Versatile Non-Invasive Biological Imaging. Biomacromolecules 2022, 23 (3), 1392-1402.
Julen Ariztia, Kamal Jouad, Valérie Jouan-Hureaux, Julien Pierson, Charlotte Collet, Bertrand Kuhnast, Katalin Selmeczi, Cédric Boura, Sandrine Lamandé-Langle, and Nadia Pellegrini-Moïse. Clickable C-Glycosyl Scaffold for the Development of a Dual Fluorescent and [18F]fluorinated Cyanine-Containing Probe and Preliminary In Vitro/Vivo Evaluation by Fluorescence Imaging. Pharmaceuticals 2022, 15 (12), 1490.