In the News

Spirituality may help reduce end-stage kidney disease risk

Researchers from Vanderbilt’s Division of Nephrology and Hypertension have identified an under-studied characteristic that may have a protective effect on end-stage kidney disease (ESKD) risk among vulnerable populations. The study, led by Devika Nair, MD, MSCI, assistant professor of Medicine within the Division of Nephrology and Hypertension, found that adults who self-identified as Black and reported high levels of spirituality had a statistically significant reduced risk for developing ESKD — independent of demographics, other psychosocial factors and lifestyle behaviors.

Geographic Variation in Women’s Colorectal Cancer Survival

A first look into where early onset mortality spikes among U.S. women. Women with early onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence, according to a study published in Clinical and Translational Gastroenterology.

Study shows healthy diet is associated with diverse and health-promoting microbiome

Scientists are just beginning to understand the impact of diet on the gut microbiome and how this interaction affects human health, but baselines must first be established to yield answers. The first large-scale, longitudinal study to evaluate this interaction among Chinese adults indicates that long-term healthy eating yields microbiome diversity and an abundance of fiber-fermenting bacteria.

Study finds breast cancer recurrence score has different implications for men

The TAILORx study published last year offered good news for women with early-stage ER-positive breast cancer who scored at intermediate risk for recurrence according to a genetic assay test. The study indicated that chemotherapy after surgery provided little advantage in overall survival for these women, so they could forgo the treatment.

Making Sense of Lung Nodules: Is It Cancer?

Six clinics across four U.S. states provided data for a newly validated clinical risk stratification model for lung cancer. The TREAT model (Thoracic Surgery, Research, Epidemiology, Diagnosis And Treatment) helps identify patients with suspicious lesions who are most likely to benefit from surgical biopsy. The aim is to mitigate unnecessary surgery for benign nodules and reduce delays for patients with early cancers.

Racial Disparities in Post-prostatectomy Mortality

In a review of 526,690 patients who underwent radical prostatectomy for localized prostate cancer, researchers from Vanderbilt University Medical Center found Black patients had significantly higher mortality rates compared to other racial and ethnic groups. Asian Americans and Pacific Islanders (AAPIs) had notably lower mortality rates than non-Hispanic whites. Hispanics had slightly lower rates than non-Hispanic whites – despite lower socioeconomic status and significant underinsurance.

Updated Guidelines for Lung Screening Could Reduce Disparities

Recommending expanded screening could help African Americans, suggests new research. The U.S. Preventive Services Task Force (USPSTF) may make recommendations to revise current lung cancer screening guidelines to reduce large differences between outcomes of African American and white patients.

Appendix cancer survival in young patients varies by race: study

Appendiceal cancer — cancer of the appendix — is a rare malignancy that is usually found during surgery for acute appendicitis. Although the rate of appendectomies has been stable over the last two decades, the incidence of malignant appendiceal cancer increased 232% in the United States.