The Scientific Working Groups (SWGs) comprise TN-CFAR members with diverse expertise in scientific discovery, clinical care, public health, biostatistics, informatics, and community engagement. The two SWGs, Personalized HIV Care (PC-SWG) and Disparities and HIV (DH-SWG), have synergistic and overlapping goals to improve HIV care at the population and individual level, respectively. These SWGs will drive research and implementation strategies to deliver on the TN-CFAR mission to reduce the burden of HIV/AIDS.