- Roumie CL, Min JY, Greevy RA, Grijalva CG, Hung AM, Liu X, Elasy T, Griffin MR. Risk of hypoglycemia following intensification of metformin treatment with insulin versus sulfonylurea. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 2016 Jan 25. PMID: 26811361 [PubMed].
Hypoglycemia remains a common life-threatening event associated with diabetes treatment. We compared the risk of first or recurrent hypoglycemia event among metformin initiators who intensified treatment with insulin versus sulfonylurea.