Andrew Wiese, Ph.D., M.P.H.

Andrew Wiese, PhD, is an Assistant Professor in the Division of Pharmacoepidemiology, Department of Health Policy at Vanderbilt University Medical Center (VUMC). My research focus is on leveraging observational studies to provide real-world evidence of the safety and efficacy of commonly used medications and vaccines, including among pregnant patients.

His current work is focused on using the TN Medicaid Mother-Child Linked Cohort (MCLC) data platform to characterize the safety of medication use for patients and infants during pregnancy and in the postpartum period, as well as using the Full TN Medicaid Cohort to examine the impact of pharmaceutical policies on medication use and medication-related outcomes. I am also interested in the development and implementation of novel research methods to characterize drug dose exposures using administrative data.

Dr. Wiese has published widely using administrative data to examine the risks of opioid analgesic use, including the risk of serious-opioid related harms among women using prescribed opioids in the postpartum period and the association between prescribed opioids and the risk of serious infections. I have also published more broadly in the field of pharmacoepidemiology related to the effectiveness of the US childhood pneumococcal conjugate vaccine program. Dr. Wiese is the Principal Investigator for a National Institute on Drug Abuse funded-career development award examining the impact of benzodiazepine restriction policies on benzodiazepine-related harms among the Full TN Medicaid Cohort.

Dr. Wiese is also a Co-Investigator on a Eunice Kennedy Shriver National Institute of Child Health & Human Development-funded study leveraging the TN MCLC data platform to examine outcomes for mothers and children affected by opioids during pregnancy using linkages to external data sources on childhood outcomes from the TN Department of Child Services and TN Early Intervention System. He is also a former appointee in the BIRCWH (Building Interdisciplinary Research Careers in Women’s Health) K12 program at VUMC.

Recent & Highlighted Research

Wiese AD, Mitchel E, Ndi D, Markus TM, Talbot HK, Schaffner W, Grijalva CG. Risk of Acute Myocardial Infarction Among Patients With Laboratory-Confirmed Invasive Pneumococcal Disease: A Self-Controlled Case Series Study. Clin Infect Dis. 2023 June 16; 76(12):2171-2177.  PubMed PMID: 36751004 Citation in REDCap PMC10273377.

Wiese AD, Grijalva CG. Burden of all-cause and organism-specific parapneumonic empyema hospitalization rates prior to the SARS-CoV-2 pandemic in the United States. Respir Med. 2023 February; 207:107111. doi:10.1016/j.rmed.2022.107111.  PubMed PMID: 36592639 Citation in REDCap PMC9803378.