Comparative analysis of PCR-based biomarker assay methods for colorectal polyp detection from fecal DNA. | Cooperative Human Tissue Network Western Division

Ausch C, Kim YH, Tsuchiya KD, Dzieciatkowski S, Washington MK, Paraskeva C, Radich J, Grady WM. Comparative analysis of PCR-based biomarker assay methods for colorectal polyp detection from fecal DNA. Clinical chemistry. 2009 Aug;55(55). 1559-63. PMID: 19541867 [PubMed]

Abstract

Aberrantly methylated genes are promising biomarkers for the detection of colon adenomas and colorectal cancers (CRCs). The optimal assay type and specific methylated genes for these assays remain to be determined.