Leena Choi, PhD

Associate Professor of Biostatistics

Office Address
2525 West End Avenue
Suite 1100, Rm 11121B
Nashville
Tennessee
37203
615-343-3497

Dr. Choi has extensive experience analyzing big data, especially in fields of electronic health records (EHRs) databases and accelerometer data. Based on her expertise in pharmacokinetics (PK) and pharmacodynamics (PD) modeling, her current research focus is to construct a system for PK/PD/pharmacogenomics studies using EHRs, which would provide the foundation for dose-optimization support system for precision medicine. Along these lines, she has been developing medication dosing extraction algorithms from EHRs, which would also benefit medication-related studies in pharmacoepidemiology. In the research using accelerometer data, she developed a new algorithm for preprocessing massive accelerometer data, which has been widely used as it was implemented in an R package as well as commercial software ActiLife.

 

Dr. Choi's research interests also include statistical methods for evaluating bioequivalence and biosimilars, clinical trial design, and the foundations of statistical inference.  She has been closely working with researchers in clinical pharmacology and doctor of nursing practice (DNP) students at Vanderbilt School of Nursing. Additionally, she has been collaborating with Vanderbilt Specialty Pharmacy for medication adherence research.