Huang GS. Transforming growth factor β1 and extracellular matrix protease expression in the uterosacral ligaments of patients with and without pelvic organ prolapse. Female pelvic medicine & reconstructive surgery. 21(21). 53-8. PMID: 25185601 [PubMed] PMCID: PMC4344824 NIHMSID: NIHMS648113.
This study was undertaken to evaluate the expression of transforming growth factor β1 (TGF-β1) and matrix metalloproteinase 9 (MMP-9), key regulators of the extracellular matrix composition, in the uterosacral ligaments (USLs) of women with pelvic organ prolapse (POP) compared with controls.