Zhou B. DNA methylation is developmentally regulated for genes essential for cardiogenesis. Journal of the American Heart Association. 2014 Jun 19;3(3). e000976. PMID: 24947998 [PubMed] PMCID: PMC4309105
DNA methylation is a major epigenetic mechanism altering gene expression in development and disease. However, its role in the regulation of gene expression during heart development is incompletely understood. The aim of this study is to reveal DNA methylation in mouse embryonic hearts and its role in regulating gene expression during heart development.