The Influenza and Other Viruses in the AcutelY Ill Network
Prime sponsor: CDC
Currently active: IVY6
VBDCC units contributing to IVY6: Design & Analysis, Data Management, Tool Development
Completed: IVY3–5
Biostatistics faculty and staff in the network have included:
- Yuwei Zhu, statistical lead
- Afan Swan
- Heather Prigmore
- Cass Johnson
- Chris Lindsell
- Kim Hart
Publications include:
- SARS-CoV-2 shedding and evolution in patients who were immunocompromised during the omicron period: A multicentre, prospective analysis (Lancet Microbe, 2024)
- Vaccine effectiveness against Influenza A - associated hospitalization, organ failure, and death: United States, 2022 - 2023 (Clinical Infectious Diseases, 2023)
- Disease severity of respiratory syncytial virus compared with COVID-19 and influenza among hospitalized adults aged ≥60 years - IVY Network, 20 U.S. states, February 2022-May 2023 (CDC Morbidity and Mortality Weekly Report, October 6, 2023)
- Comparison of mRNA vaccine effectiveness against COVID-19-associated hospitalization by vaccination source: Immunization information systems, electronic medical records, and self-report-IVY Network, February 1–August 31, 2022 (Vaccine, 2023)
- Early serial echocardiographic and ultrasonographic findings in critically ill patients with COVID-19 (CHEST Critical Care, 2023)
- Changing severity and epidemiology of adults hospitalized with coronavirus Disease 2019 (COVID-19) in the United States after introduction of COVID-19 vaccines, March 2021–August 2022 (Clinical Infectious Diseases - Editor's Choice, 2023)
- Total and subgenomic RNA viral load in patients infected with SARS-CoV-2 Alpha, Delta, and Omicron variants (Journal of Infectious Diseases, 2023)
- Protection of messenger RNA vaccines against hospitalized Coronavirus Disease 2019 in adults over the first year following authorization in the United States (Clinical Infectious Diseases, 2023)
- Absolute and relative vaccine effectiveness of primary and booster series of COVID-19 vaccines (mRNA and adenovirus vector) against COVID-19 hospitalizations in the United States, December 2021-April 2022 (Open Forum Infectious Diseases, 2023)
- Effectiveness of monovalent mRNA vaccines against COVID-19-associated hospitalization among immunocompetent adults during BA.1/BA.2 and BA.4/BA.5 predominant periods of SARS-CoV-2 Omicron variant in the United States - IVY Network, 18 states, December 26, 2021-August 31, 2022 (CDC Morbidity and Mortality Weekly Report, October 21, 2022)
- Effectiveness of the Ad26.COV2.S (Johnson & Johnson) coronavirus disease 2019 (COVID-19) vaccine for preventing COVID-19 hospitalizations and progression to high disease severity in the United States (Clinical Infectious Diseases, 2022)
- Effectiveness of mRNA vaccines against COVID-19 hospitalization by age and chronic medical conditions burden among immunocompetent US adults, March-August 2021 (Journal of Infectious Diseases, 2022)
- Effectiveness of severe acute respiratory syndrome Coronavirus 2 messenger RNA vaccines for preventing Coronavirus Disease 2019 hospitalizations in the United States (Clinical Infectious Diseases, 2022)
- Clinical severity of, and effectiveness of mRNA vaccines against, COVID-19 from Omicron, Delta, and Alpha SARS-CoV-2 variants in the United States: Prospective observational study (BMJ, 2022)
- Effectiveness of a third dose of Pfizer-BioNTech and Moderna vaccines in preventing COVID-19 hospitalization among immunocompetent and immunocompromised adults - United States, August-December 2021 (CDC Morbidity and Mortality Weekly Report, January 28, 2022)
- Association between mRNA vaccination and COVID-19 hospitalization and disease severity (JAMA, 2021)
Press:
- Vaccine effectiveness research continues to grow (VUMC Reporter, January 26, 2023)
- Bivalent booster vaccine effective in preventing COVID-19 hospitalization in older adults (VUMC Reporter, December 16, 2022)
- Additional COVID vaccine helps protect transplant patients (VUMC Reporter, April 13, 2022)
- Grant boosts vaccine effectiveness research (VUMC Reporter, January 6, 2022)
- About half of health care workers positive for COVID-19 by serology have no symptoms (VUMC Reporter, July 9, 2020)