The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - May 8th, 2023
- Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis. Weindel C, et al. in Cell, August 18, 2022
- CTCF mediates CD8+ effector differentiation through dynamic redistribution and genomic reorganization. Liu J, et al. in Journal of Experimental Medicine, April 23, 2023
- Exploring Masses and Internal Mass Distributions of Single Carboxysomes in Free Solution Using Fluorescence and Interferometric Scattering in an Anti-Brownian Trap. Lavania A, et al. in The Journal of Physical Chemistry B, October 25, 2022
- STAT3 regulates CD8+ T cell differentiation and functions in cancer and acute infection. Sun Q, et al. in Journal of Experimental Medicine, April 3, 2023
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins. Oh C, et al. in Cell Reports, November 22, 2022
Recommended Reading - February 5th, 2023
- Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation. Hata M, et al. in Science, January 6, 2023
- Functional T cells are capable of supernumerary cell division and longevity. Soerens A, et al. in Nature, December 5, 2022
- Chlamydia repurposes the actin-binding protein EPS8 to disassemble epithelial tight junctions and promote infection. Dolat L, et al. in Cell Host & Microbe, December 14, 2022
- Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses. Cuesta S, et al. in Cell Host & Microbe, November 9, 2022
- Fetal and maternal NLRP3 signaling is required for preterm labor and birth. Motomura K, et al. in The Journal of Clinical Investigation Insights, August 22, 2022
Recommended Reading - January 15th, 2023
- Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus. Mackensen A, et al. in Nature Medicine, September 15, 2022
- Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Hagan T, et al. in Nature Immunology, October 21, 2022
- Engineered cell entry links receptor biology with single-cell genomics. Yu B, et al. in Cell, December 22, 2022
- Mycobiota and diet-derived fungal xenosiderophores promote Salmonella gastrointestinal colonization. Santus W, et al. in Nature Microbiology, November 21, 2022
- Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules. Lei X, et al. in Journal of Experimental Medicine, July 6, 2022
Recommended Reading - October 16, 2022
- Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis. Doke T, et al. in Nature Immunology, May 12, 2022
- The metastatic spread of breast cancer accelerates during sleep. Diamantopoulou Z, et al. in Nature, June 22, 2022
- A family of unusual immunoglobulin superfamily genes in an invertebrate histocompatibility complex. Heune A, et al. in PNAS, September 26, 2022
- Innate type 2 immunity controls hair follicle commensalism by Demodex mites. Ricardo-Gonzalez R, et al. in Cell Immunity, August 30, 2022
- Regulation of Klebsiella pneumoniae mucoidy by the bacterial tyrosine kinase Wzc. Khadka S, et al. in bioRxiv, June 5, 2022
Recommended Reading - September 4, 2022
- BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Cao Y, et al. in Nature, June 17, 2022
- pH sensing controls tissue inflammation by modulating cellular metabolism and endo-lysosomal function of immune cells. Chen X, et al. in Nature Immunology, June 6, 2022
- Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation. Campos-Mora M, et al. in Journal of Extracellular Vesicles, June 8, 2022
- Patterns and Predictors of Failure in Recurrent or Refractory Large B-Cell Lymphomas After Chimeric Antigen Receptor T-Cell Therapy. Figura N, et al. in International Journal of Radiation Oncology*Biology*Physics, December 1, 2021
- Global, distinctive, and personal changes in molecular and microbial profiles by specific fibers in humans. Lancaster S, et al. in Cell Host & Microbe, April 27, 2022
Recommended Reading - August 7th, 2022
- Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3. Grebinoski S, et al. in Nature Immunology, May 26, 2022
- Mapping the developing human immune system across organs. Suo C, et al. in Science, June 7, 2022
- Pregnancy enables antibody protection against intracellular infection. Erickson J, et al. in Nature, June 8, 2022
- Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1. McCulloch J, et al. in Nature Medicine, February 28, 2022
- Tissue remodeling by an opportunistic pathogen triggers allergic inflammation. Agaronyan K, et al. in Immunity, May 10, 2022
Recommended Reading - April 10, 2022
- Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. McCallum M, et al. in Science, January 25, 2022
- TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. Chaurio R, et al. in Immunity, January 11, 2022
- KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Jing L, et al. in Science, March 8, 2022
- Single-cell transcriptional profiling informs efficient reprogramming of human somatic cells to cross-presenting dendritic cells. Fabio R, et al. in Science Immunology, March 4, 2022
- Rare and localized events stabilize microbial community composition and patterns of spatial self-organization in a fluctuating environment. Ciccarese D, et al. in The ISME Journal, January 25, 2022
Recommended Reading - January 9th, 2022
- Mapping the cellular origin and early evolution of leukemia in Down syndrome. Wagenblast E, et al. in Science, July 9, 2021
- Arthritis flares mediated by tissue-resident memory T cells in the joint. Chang M, et al. in Cell Reports, October 26, 2021
- An autoimmune stem-like CD8 T cell population drives type 1 diabetes. Gearty S, et al. in Nature, November 30, 2021
- Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer. Overacre-Delgoffe A, et al. in Immunity, December 2, 2021
- Heme-Dependent Siderophore Utilization Promotes Iron-Restricted Growth of the Staphylococcus aureus hemB Small-Colony Variant. Batko I, et al. in Journal of Bacteriology, November 19, 2021
Recommended Reading - December 19, 2021
- Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy. Bentires-Alj M et al. in Nature, June 2, 2021
- Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. Jul`e A, et al. in JCI Insight, September 22, 2021
- The lungfish cocoon is a living tissue with antimicrobial functions. Heimroth R, et al. in Science Advances, November 17, 2021
- Human gut bacterial metabolism drives Th17 activation and colitis. Alexander M, et al. in Cell Host & Microbe, November 24, 2021
- γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans. Chu T, et al. in PLOS Pathogens, December 6, 2021
Recommended Reading - November 14, 2021
- Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers. Caushi J, et al. in Nature Biotechnology, July 21, 2021
- An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer. Voabil P, et al. in Nature, July 8, 2021
- Obesity results in adipose tissue T cell exhaustion. Porshe C, et al. in Science, April 22, 2021
- Diet-regulated production of PDGFcc by macrophages controls energy storage. Cox N, et al. in Nature Ecology & Evolution, July 2, 2021
- Maturation of the matrix and viral membrane of HIV-1. Qu K, et al. in Cell Host & Microbe, August 6, 2021
