The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - March 5th, 2023
- CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor. Prokhnevska N, et al. in Immunity, December 21, 2022
- Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states. Ma P, et al. in Cell, February 16, 2023
- Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks. Amato K, et al. in Nature Communications, June 14, 2022
- The maternal prenatal and offspring early-life gut microbiome of childhood asthma phenotypes. Lee-Sarwar K, et al. in Allergy, September 15, 2022
- A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli. Birkholz E, et al. in Cell Reports, August 16, 2022
Recommended Reading - February 5th, 2023
- Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation. Hata M, et al. in Science, January 6, 2023
- Functional T cells are capable of supernumerary cell division and longevity. Soerens A, et al. in Nature, December 5, 2022
- Chlamydia repurposes the actin-binding protein EPS8 to disassemble epithelial tight junctions and promote infection. Dolat L, et al. in Cell Host & Microbe, December 14, 2022
- Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses. Cuesta S, et al. in Cell Host & Microbe, November 9, 2022
- Fetal and maternal NLRP3 signaling is required for preterm labor and birth. Motomura K, et al. in The Journal of Clinical Investigation Insights, August 22, 2022
Recommended Reading - January 15th, 2023
- Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus. Mackensen A, et al. in Nature Medicine, September 15, 2022
- Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Hagan T, et al. in Nature Immunology, October 21, 2022
- Engineered cell entry links receptor biology with single-cell genomics. Yu B, et al. in Cell, December 22, 2022
- Mycobiota and diet-derived fungal xenosiderophores promote Salmonella gastrointestinal colonization. Santus W, et al. in Nature Microbiology, November 21, 2022
- Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules. Lei X, et al. in Journal of Experimental Medicine, July 6, 2022
Recommended Reading - December 11, 2022
- Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes. Ataide M, et al. in Immunity, October 11, 2022
- Gut bacterial nutrient preferences quantified in vivo. Zeng X, et al. in Cell Reports, September 1, 2022
- Protein Kinase CK2 Controls CD8+ T Cell Effector and Memory Function during Infection. Yang W, et al. in The Journal of Immunology, September 1, 2022
- Design, construction, and in vivo augmentation of a complex gut microbiome. Cheng A, et al in Cell, September 15, 2022
- Actin cytoskeleton remodeling primes RIG-I-like receptor activation. Acharya D, et al. in Cell, September 15, 2022
Recommended Reading - November 6th, 2022
- TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors. Wang W, et al. in Nature Immunology, June 20, 2022
- Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers. Aavaloaei A, et al. in Cell Reports, August 16, 2022
- Evolution of immune genes is associated with the Black Death. Klunk J, et al. in Nature, October 19, 2022
- Neutrophil Recruitment in Pneumococcal Pneumonia. Palmer C & Kimmey J in Frontiers in Cellular and Infection Microbiology, May 13, 2022
- A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans. Denham S, et al. in Cell Host & Microbe, September 12, 2022
Recommended Reading - October 16, 2022
- Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis. Doke T, et al. in Nature Immunology, May 12, 2022
- The metastatic spread of breast cancer accelerates during sleep. Diamantopoulou Z, et al. in Nature, June 22, 2022
- A family of unusual immunoglobulin superfamily genes in an invertebrate histocompatibility complex. Heune A, et al. in PNAS, September 26, 2022
- Innate type 2 immunity controls hair follicle commensalism by Demodex mites. Ricardo-Gonzalez R, et al. in Cell Immunity, August 30, 2022
- Regulation of Klebsiella pneumoniae mucoidy by the bacterial tyrosine kinase Wzc. Khadka S, et al. in bioRxiv, June 5, 2022
Recommended Reading - September 4, 2022
- BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Cao Y, et al. in Nature, June 17, 2022
- pH sensing controls tissue inflammation by modulating cellular metabolism and endo-lysosomal function of immune cells. Chen X, et al. in Nature Immunology, June 6, 2022
- Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation. Campos-Mora M, et al. in Journal of Extracellular Vesicles, June 8, 2022
- Patterns and Predictors of Failure in Recurrent or Refractory Large B-Cell Lymphomas After Chimeric Antigen Receptor T-Cell Therapy. Figura N, et al. in International Journal of Radiation Oncology*Biology*Physics, December 1, 2021
- Global, distinctive, and personal changes in molecular and microbial profiles by specific fibers in humans. Lancaster S, et al. in Cell Host & Microbe, April 27, 2022
Recommended Reading - August 7th, 2022
- Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3. Grebinoski S, et al. in Nature Immunology, May 26, 2022
- Mapping the developing human immune system across organs. Suo C, et al. in Science, June 7, 2022
- Pregnancy enables antibody protection against intracellular infection. Erickson J, et al. in Nature, June 8, 2022
- Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1. McCulloch J, et al. in Nature Medicine, February 28, 2022
- Tissue remodeling by an opportunistic pathogen triggers allergic inflammation. Agaronyan K, et al. in Immunity, May 10, 2022
Recommended Reading - July 10th, 2022
- Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice. Hunt A, et al. in Science Translational Medicine, April 12, 2022
- Intramuscular AZD7442 (Tixagevimab– Cilgavimab) for Prevention of Covid-19. Levin MJ, et al. in The New England Journal of Medicine, April 20, 2022
- Neoantigen quality predicts immunoediting in survivors of pancreatic cancer. Luksza M, et al. in Nature, May 19, 2022
- Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids. Le HH, et al. in Cell Host & Microbe, June 8, 2022
- Extracellular vesicles from lung tissue drive bone marrow neutrophil recruitment in inflammation. Liu B, et al. in Journal of Extracellular Vesicles, May 20, 2022
Recommended Reading - June 7th, 2022
- Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation. Cautivo K, et al. in Immunity, February 8, 2022
- Immunosuppression broadens evolutionary pathways to drug resistance and treatment failure during Acinetobacter baumannii pneumonia in mice. Huo W, et al. in Nature Microbiology, May 26, 2022
- Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces. Maeda K, et al. in Cell Host & Microbe, February 9, 2022
- Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus. Shinzawa M, et al. in Nature Immunology, April 29, 2022
- Human gut bacteria produce ΤΗ17-modulating bile acid metabolites. Paik D, et al. in Nature, March 16, 2022
