Bradley W. Richmond, M.D., Ph.D.
Chronic obstructive pulmonary disease and deployment-related respiratory disease
Dr. Richmond received his undergraduate degree from the University of Evansville in 2003 and his M.D. from the University of Louisville in 2007. He then completed a residency in internal medicine, a clinical fellowship in pulmonary and critical care medicine, and a Ph.D. in cell and developmental biology at Vanderbilt University. Dr. Richmond’s research focuses on how chronic inflammation alters epithelial differentiation in the airways and the consequences of altered epithelial differentiation on host defense and microbial community structure.
The airway epithelium forms a critical line of defense between the lungs and the outside world. Multiple cell types in the airway epithelium function in a coordinated manner to prevent microbial penetration into the lungs while maintaining tolerance to normal airway flora. Alterations in the cellular composition of the airway epithelium are common in diseases such as chronic obstructive pulmonary disease (COPD), and may result in breakdown of this mucosal immunobarrier. The Richmond lab utilizes both in vitro and in vivo model systems to understand why epithelial differentiation is altered in COPD and other airway diseases and whether these alterations affect host-microbial interactions in ways that contribute to disease. Dr. Richmond is currently supported by a K08 award from the National Heart, Lung, and Blood Institute of the NIH.