Structural Biology of virulence factors, host-pathogen relationship, and cytoskeletal regulation
The Spiller lab is a structural biology lab using protein crystallography as our main structural tool. Current questions being addressed include protein phosphatases, bacterial pathogenesis, and the host immune response. Potential rotation projects will be designed to meet the interests of the students, but will generally fall into one of the aforementioned topics. Of particular current interest is extending our work on bacterial pathogenesis.