July 25, 2005: IV NAC Protocol (Prescott Protocol)

The FDA has approved the administration of IV NAC (mucomyst).

Loading Dose:  NAC 150mg/kg in D5W 200cc
                           Infuse over one hour

Followed by Continuous Infusion #1: 
                           NAC 50mg/kg in D5W 500cc
                           Infuse over 4 hours
Followed by Continuous Infusion #2:
                            NAC 100mg/kg in D5W 1000cc
                            Infuse over 16 hours

Acetadote is the only FDA-approved formulation currently available for intravenous administration.

Reactions to IV NAC are few and include flushing, hypotension, and bronchospasm and are generally related to the rate of infusion.

The FDA has approved the administration of IV NAC (mucomyst).

Loading Dose:  NAC 150mg/kg in D5W 200cc
                           Infuse over one hour

Followed by Continuous Infusion #1: 
                           NAC 50mg/kg in D5W 500cc
                           Infuse over 4 hours
Followed by Continuous Infusion #2:
                            NAC 100mg/kg in D5W 1000cc
                            Infuse over 16 hours

Acetadote is the only FDA-approved formulation currently available for intravenous administration.

Reactions to IV NAC are few and include flushing, hypotension, and bronchospasm and are generally related to the rate of infusion.