Adventure Travel Guide to the Microbial World

We are a group of faculty and first year graduate students who are embarking on a travel expedition into the microbial world.  Check this site for a description of what we learn and see along the journey.   You can also follow us on Twitter!  @ClassMicro

We welcome your constructive feedback!

A Tick's Meal

            On episode 258 of the podcast “This Week in Microbiology”, Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt discussed two main topics focused on anti-genetic variation within dengue virus serotypes and how a novel mRNA vaccine could induce antibodies against tick proteins to prevent transmission of Lyme disease.

A Microbe You May Not Know

On this episode of the podcast “This Week in Microbiology” Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt discussed the research paper from the National Institute of Allergy and Infectious Disease (NIAID) by Myles et al. titled “Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair” which discussed the skin microbiome and atopic dermatitis.

Turducken antibiotics

In the podcast “This Week in Microbiology” the hosts Vincent Racaniello and Michael Schmidt discussed a scientific paper on a novel synthetic dual drug called sideromycin that is used to combat Gram-negative bacteria.

Let’s Get Our Hands Dirty

The rise of antibiotic resistance constitutes a very real and growing global health threat.   Between 2000 and 2020, only 24 new antibiotics were approved by the FDA, an alarming decrease from the 63 antibiotics approved in the preceding twenty years1. However, there is still hope for solutions to this crisis.

TWIM: Exosomes in your nose and in your gut

In the podcast “Exosomes in your nose and in your gut” in the series “This Week in Microbiology”, hosts Michael Schmidt, Michele Swanson, and Vincent Racaniello talk primarily about two recent articles (Schmidt et al., 2019). The first article focuses on the immune response in nasal epithelial cells to invading pathogens.

Circ du RNA

In the “Circ du RNA” episode of the podcast This Week in Virology, Racaniello and colleagues interview Patrick Moore on his investigation into circular RNAs (circRNA) made by Epstein-Barr virus (EBV) and Kaposi’s sarcoma herpesvirus (KSHV). Specifically, they delineate functions of the viral circRNAs, how they are formed, and some potential applications in EBV- and KSHV-related cancer diagnostics.

Bacteria, colon cancer and fire blight

Recent studies have demonstrated the potential of a fecal microbiota transplantation (FMT) in modulating immunotherapeutic outcomes of colorectal cancer (CRC) subjects (Rosshart et al., 2017).