Research Networks

We are pleased to participate in important national research networks that provide CHSR investigators an opportunity to lead or collaborate in multi-center studies.

Stakeholders, Technology, and Research Clinical Research Network (STAR CRN)

VUMC is the lead site for this PCORI-funded research network which supports comparative effectiveness research, stakeholder engagement, and the innovative use of technology to enhance and change the paradigm for patient-centered outcomes research. Russell Rothman, MD MPP, is the Principal Investigator of the STAR CRN, which was previously called the Mid-South Clinical Data Research Network. The network engages hospitals and clinics across the country and has data on more than 12 million patients.

The STAR CRN consists of:

  • Vanderbilt University Health System
  • Meharry Medical College
  • Vanderbilt Healthcare Affiliated Network (VHAN)
  • University of North Carolina Chapel Hill
  • Duke University
  • Health Sciences South Carolina
  • Wake Forest
  • Mayo Clinic

Hospital Medicine Reengineering Network (HOMERuN)

VUMC is a founding member of the HOMERuN collaborative, which engages hospitalists, researchers, and hospital medicine groups at leading medical centers nationwide, accelerating the discovery and swift implementation of quality care improvements. Sunil Kripalani, MD, MSc, and Eduard Vasilevskis, MD, MPH, lead VUMC’s participation.

Projects include multi-site studies on the preventability of hospital readmissions; incidence, causes, and risk factors for diagnostic error in hospital settings (UPSIDE); and a large clinical collaborative on COVID-19. HOMERuN maintains an active Patient & Family Advisory Council, established under a Eugene Washington Award from PCORI.


Deprescribe logo

The goal of the US Deprescribing Research Network (USDeN) is to develop and disseminate evidence about deprescribing for older adults, and in doing so, to help improve medication use among older adults and the outcomes that are important to them. Funded by the National Institute on Aging, the network is a community of people united by a shared interest in improving research on deprescribing for older adults. The network’s key activities are designed to provide resources and supports that will catalyze expansion of the quality, quantity, and ultimate impact of deprescribing research, and to promote mutual learning and collaboration that is essential to this goal.