JAMIA: DDIWAS: High-Throughput Electronic Health Record-Based Screening of Drug-Drug Interactions

Researchers from Vanderbilt University Medical Center's Department of Biomedical Informatics and Medicine, Vanderbilt's School of Medicine, and the University of South Dakota Sanford School of Medicine developed and evaluated Drug-Drug Interaction Wide Association Study (DDIWAS). This novel method detects potential drug-drug interactions (DDIs) by leveraging data from the electronic health record (EHR) allergy list. 

In this new study, published in JAMIA on March 13, 2021, the researchers demonstrated the value of incorporating information mined from existing allergy lists to detect DDIs in a real-world clinical setting. Since allergy lists are routinely collected in EHRs, DDIWAS has the potential to detect and validate DDI signals across institutions. 

DBMI's Patrick Wu, Scott Nelson, Juan Zhao, Qingxia "Cindy" Chen, Dan Roden, Josh Denny, and Wei-Qi Wei are co-authors of the study. Read more here.