Henry Charles Manning, Ph.D.

Director, Vanderbilt Center for Molecular Probes and Molecular Imaging Research
VICC Director of Cancer Imaging Research
Ingram Associate Professor of Cancer Research
Professor of Radiology and Radiological Sciences
Professor of Biomedical Engineering
Professor in Neurological Surgery
Professor of Chemistry

MCN AAA-3115 VUIIS
1161 21st. Avenue South
Nashville
Tennessee
37232-2310
615-322-3793

Non-invasive molecular imaging metrics to assess disease progression and response to therapy

My interests are Molecular Imaging Probe Development, PET, Radiochemistry, Medicinal Chemistry, Drug Discovery, and HTS. Our lab develops new imaging biomarkers of cancer and other human diseases.

Research Description

Our multi-disciplinary research program involves the development, validation, and translation of non-invasive molecular imaging metrics to assess disease progression and response to therapy. Projects within our program emphasize molecular imaging of cancer, and notably imaging-based assessment of response to anti-cancer pharmaceuticals in colorectal and breast cancer. We are actively engaged in advancing novel methods to image molecular events in both humans and animal models that include receptor expression, proliferation, angiogenesis, and apoptosis. Among these methods include validation of imaging probes for novel applications, as well as high-throughput small-molecule discovery to develop novel imaging compounds.

Publications on PubMed.gov