Training: METP

The Molecular Endocrinology Training Program (METP) is a combined predoctoral and postdoctoral training program that began in 1988 and is now in its 34th year of NIDDK funding. The METP was directed by Dr. Daryl Granner from 1988-2004 and has been directed by Dr. Richard O'Brien since 2004.


The METP has a highly successful record in achieving its stated goal, namely the training of individuals for careers in molecular endocrinology-related research. 200+ pre- and postdoctoral that have been supported by the METP over the duration of the program, many have gone on to obtain academic positions, work in biotech/pharmaceutical industries, hold technical positions in research laboratories, pursue clinical practice, teach, go into business, or work as science writers, government researchers, university administrators, or as non-governmental science or health agency staff.




Welcome to the website for the Vanderbilt Molecular Endocrinology Training Program (METP). Molecular endocrinology includes ligand-receptor interactions, signal generation and transduction, the molecular actions of intracellular signals, and the cellular and physiological consequences of hormone action. Vanderbilt has a long tradition of excellent research in these areas. Indeed, some of the important fundamental concepts (cAMP as a second messenger, Earl Sutherland; growth factor receptors as tyrosine kinases, Stanley Cohen; the regulation of glucose uptake by insulin, C.R. Park and Tetsuro Kono) were established here. Sutherland and Cohen both won the Nobel Prize in Physiology or Medicine for their discoveries.

The field of molecular endocrinology is clearly of central relevance to multiple human diseases, most notably obesity and diabetes. Continued progress towards understanding and curing these and many other diseases requires that the next generation of scientists be given the knowledge and skills to perform independent research. Providing this training is the goal of the METP.

The METP supports eight pre-doctoral and four post-doctoral trainees each year. Funding covers the cost of stipends, health care and travel to attend appropriate research meetings. For pre-doctoral trainees funding also covers the cost of tuition.

The Molecular Endocrinology Training Program (METP) is supported by NIH grant T32 DK07563 and by the Vanderbilt Diabetes Research Center (NIH grant DK20593).

METP Publications