Dawn C. Newcomb, Ph.D.
Role of sex hormones in inflammation in asthma
Our laboratory is focused on determining the role of sex hormones on innate lymphoid cell and T cell differentiation and cytokine expression, using asthma as our disease model. To study this, we utilize lymphocytes from the blood of healthy and asthmatic individuals as well as mouse models which mimic asthma. Findings from our laboratory will be important in determining why women are more likely to have asthma as adults compared to men and may provide new potential therapeutic targets for treating airway inflammation.