Services

  • The CQS Biostatistics team works with School of Medicine investigators to:

    • define objectives and endpoints
    • analyze pilot data
    • select an appropriate design
    • compute an adequate sample size with concern for the clinical as well as statistical significance
    • estimate the time required to accrue the total patient population
    • specify the statistical methods
    • prepare statistical sections of the grant and protocol applications

    Its members endeavor to:

    • provide consultative services for School of Medicine investigators in the statistical design, conduct, and analysis of studies
    • collaborate in funded research efforts initiated by School of Medicine laboratory and clinical investigators, by providing statistical expertise in study design, power and sample size analysis; data analysis; interpretation of results; and writing of manuscripts
    • provide relational database design, data tracking, forms, queries, and reports for investigator-initiated clinical trial databases or laboratory study databases
    • develop and evaluate statistical methods for experimental design and data analysis
    • work with Vanderbilt's Clinical Trials Shared Resource (CTSR) to maintain data quality control and ensure timely data capture
    • train investigators in research design and data analysis through seminars, short statistical workshops, and individual sessions on statistical methods

     

    Biostatistics Program Leader

    Tatsuki Koyama, PhD
    Associate Professor of Biostatistics

  • The CQS Bioinformatics team works with School of Medicine investigators to:

    • define objectives and endpoints
    • provide consultative services for bioinformatics-related project design
    • provide consultative services for bioinformatics data analysis
    • provide consultative services for database and software development
    • analyze pilot data
    • prepare the bioinformatics sections of grant and protocol applications

    Its members endeavor to:

    • provide consultative services for Vanderbilt Medical School investigators in bioinformatics data analysis
    • collaborate in funded research efforts initiated by Vanderbilt Medical School laboratory and clinical investigators, by providing bioinformatics expertise in data analysis; data interpretation; hypothesis generating; and writing of manuscripts
    • develop and evaluate computational methods and software tools for bioinformatics data analysis
    • train Vanderbilt Medical School investigators in bioinformatics resources and data analysis methods through seminars, short workshops, and individual sessions

     

    Bioinformatics Program Leader

    Qi Liu, PhD
    Associate Professor of Biostatistics
     

  • The CQS Systems Biology team works with School of Medicine investigators to:

    • define objectives and endpoints
    • provide consultative services for omics (genomics, transcriptomics, and proteomics) data analysis
    • provide consultative services for data integration and pathway and network analysis
    • provide consultative services for systems biology databases and software packages
    • analyze pilot data
    • prepare computational systems biology sections of the grant and protocol applications

    Its members endeavor to:

    • provide consultative services for Vanderbilt Medical School investigators in data integration and systems biology
    • collaborate in funded research efforts initiated by Vanderbilt Medical School laboratory and clinical investigators, by providing systems biology expertise in data integration; data analysis; data interpretation; hypothesis generating; and writing of manuscripts
    • develop and evaluate computational methods for data integration and analysis
    • train investigators in systems biology resources and data analysis methods through seminars, short workshops, and individual sessions

    Systems Biology Program Leader

    Vito Quaranta, MD
    Professor of Biochemistry and Pharmacology
    Director, Quantitative Systems Biology Center

  • The CQS Data Coordinating Services (DCS) team works with Medical School investigators to:

    • define technical requirements and expectations for data management, including database design and routine data reporting
    • develop appropriate data dictionary and data entry manual to ensure comprehensive documentation of data elements in support of data collection goals
    • develop custom data collection, management, and storage solutions, appropriate to the needs of each project
    • maintain ongoing communication and service to provide training on data entry, ensure IRB compliance, address any issues or bugs, and ensure data quality control
    • provide routine and custom data reports and summary statistics as data accrues

    The members of the CQS DCS endeavor to:

    • provide data management expertise to fill this critical gap in many research programs
    • assist in improving the quality and efficiency of biomedical research, by providing project-centric data management solutions
    • improve the quantity and quality of knowledge gained from data, by providing data management solutions that promote and optimize data integrity

    DCS Program Leader

    Lynne D. Berry, PhD 
    Deputy Director, CQS
    Vice Chair of Informatics & Collaborative Programs, Department of Biostatistics

  • The CQS Health Services Research team provides analytical support to Vanderbilt HSR and outcome research investigators:

    • consult to optimize study design and performance
    • compute sample size and estimate analytical power
    • develop plans for appropriate statistical analysis
    • perform statistical analysis
    • execute interim analyses
    • write statistical results for publication
    • develop publication quality tables and figures
    • ensure high-quality data collection collaborating with CQS Data Coordinating Services
    • provide education in fundamentals in biostatistics in HSR and outcome research and introduction to basic epidemiological concepts
    • provide expertise in utilizing large observational databases for epidemiological studies

     

    HSR Program Leader

    Fei Ye, PhD, MSPH
    Associate Professor of Biostatistics and Medicine