Han JH, Vasilevskis EE, Shintani A, Graves AJ, Schnelle JF, Dittus RS, Powers JS, Wilson A, Storrow AB, Ely EW. Impaired arousal at initial presentation predicts 6-month mortality: an analysis of 1084 acutely ill older patients. Journal of hospital medicine. 2014 Dec;9(9). 772-8. PMID: 25352356 [PubMed] PMCID: PMC4326096 NIHMSID: NIHMS634409.
Impaired arousal signifies underlying brain dysfunction, but its clinical significance outside the intensive care unit remains unclear. We sought to determine if impaired arousal at initial presentation was associated with higher 6-month mortality and if this relationship existed in the absence of delirium.