Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science.

Denny JC, Ritchie MD, Crawford DC, Schildcrout JS, Ramirez AH, Pulley JM, Basford MA, Masys DR, Haines JL, Roden DM. Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science. Circulation. 2010 Nov 16;122(122). 2016-21. PMID: 21041692 [PubMed] PMCID: PMC2991609 NIHMSID: NIHMS244204.

Abstract

Recent genome-wide association studies in which selected community populations are used have identified genomic signals in SCN10A influencing PR duration. The extent to which this can be demonstrated in cohorts derived from electronic medical records is unknown.